The Price of Progress: Funding and Financing Alzheimer\u27s Disease Drug Development [PDF]
, 2018 Introduction Advancing research and treatment for Alzheimer\u27s disease (AD) and the search for effective treatments depend on a complex financial ecosystem involving federal, state, industry, advocacy, venture capital, and philanthropy funding ...
Cummings, Jeffrey +2 more
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National Center for Autonomous Technologies (NCAT)
, 2022 The National Center for Autonomous Technologies (NCAT) was formulated through the National Science Foundation’s Advanced Technological Education (NSF ATE) program in 2019. As the first national ATE center in autonomous technologies, NCAT is crafting, adapting, and implementing educational resources to support K-12 educators, and two-year college ...
Beck, Jonathan, Bergee, Anton
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Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial. [PDF]
, 2015 Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin ...
Bild, Diane E +14 more
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Science-Business eXchange, 2014 Comments from Christopher Austin, director of the National Center for Advancing Translational Sciences, on how the center is delivering on its promise to overcome roadblocks and accelerate the translational process.
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NCATS gains first chief and positions for industry partnerships [PDF]
Nature Medicine, 2012 exaly +2 more sources
Canvass: a crowd-sourced, natural-product screening library for exploring biological space [PDF]
, 2018 NCATS thanks Dingyin Tao for assistance with compound characterization. This research was supported by the Intramural Research Program of the National Center for Advancing Translational Sciences, National Institutes of Health (NIH). R.B.A.
Andrade, Rodrigo B. +94 more
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Exploring NCATS In-House Biomedical Data for Evidence-based Drug Repurposing
PLOS ONE, 2023 AbstractDrug repurposing is a strategy for identifying new uses of approved or investigational drugs that are outside the scope of the original medical indication. Even though many repurposed drugs have been found serendipitously in the past, the increasing availability of large volumes of biomedical data has enabled more systemic, data-driven ...
Fang Liu +6 more
openaire +5 more sources
Journal of Biomedical Semantics, 2020 Background The Genetic and Rare Diseases (GARD) Information Center was established by the National Institutes of Health (NIH) to provide freely accessible consumer health information on over 6500 genetic and rare diseases.
Qian Zhu +5 more
doaj +1 more source
Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury
Redox Biology, 2023 NADPH oxidases (NOX's), and the reactive oxygen species (ROS) they produce, play an important role in host defense, thyroid hormone synthesis, apoptosis, gene regulation, angiogenesis and other processes.
Hannah Mason +20 more
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Genetic modifiers of ambulation in the cooperative international Neuromuscular Research Group Duchenne natural history study [PDF]
, 2015 OBJECTIVE: We studied the effects of LTBP4 and SPP1 polymorphisms on age at loss of ambulation (LoA) in a multiethnic Duchenne muscular dystrophy (DMD) cohort.
Andreone, Luz +13 more
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