Developing the Quantitative Histopathology Image Ontology : A case study using the hot spot detection problem [PDF]
, 2017 Interoperability across data sets is a key challenge for quantitative histopathological imaging. There is a need for an ontology that can support effective merging of pathological image data with associated clinical and demographic data.
Doyle, Scott +6 more
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Direct Type I IFN but Not MDA5/TLR3 Activation of Dendritic Cells Is Required for Maturation and Metabolic Shift to Glycolysis after Poly IC Stimulation [PDF]
, 2014 We thank the Rockefeller University Center for Clinical and Translational Science (UL1 TR000043 NCATS, NIH) for technical ...
A Le Bon +50 more
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Computational and Structural Biotechnology Journal, 2016 Microphysiological systems (organs-on-chips, tissue chips) are devices designed to recapitulate human physiology that could be used to better understand drug responses not easily addressed using other in vivo systems or in vitro animal models.
Christine A. Livingston +2 more
doaj +1 more source
Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey. [PDF]
, 2020 Primary Immune Regulatory Disorders (PIRD) are an expanding group of diseases caused by gene defects in several different immune pathways, such as regulatory T cell function.
Allenspach, Eric J +59 more
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Results of a UK industrial tribological survey
, 2013 During the summer of 2012, the National Centre for Advanced Tribology at Southampton (nCATS) undertook a UK-wide industrial tribological survey in order to assess the explicit need for tribological testing within the UK.
Harvey, T.J. +3 more
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Identification of a G-Protein-Independent Activator of GIRK Channels
Cell Reports, 2020 Summary: G-protein-gated inwardly rectifying K+ (GIRK) channels are essential effectors of inhibitory neurotransmission in the brain. GIRK channels have been implicated in diseases with abnormal neuronal excitability, including epilepsy and addiction ...
Yulin Zhao +10 more
doaj +1 more source
In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma. [PDF]
, 2016 The long-term overall survival of Ewing sarcoma (EWS) patients remains poor; less than 30% of patients with metastatic or recurrent disease survive despite aggressive combinations of chemotherapy, radiation and surgery.
Alturkmani, Hani +11 more
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Acta Neuropathologica Communications, 2020 Molecular biomarkers provide both diagnostic and prognostic results for patients with diffuse glioma, the most common primary brain tumor in adults.
Thidathip Wongsurawat +9 more
doaj +1 more source
Research-based versus clinical serum creatinine measurements and the association of acute kidney injury with subsequent kidney function: findings from the Chronic Renal Insufficiency Cohort study. [PDF]
, 2020 Background:Observational studies relying on clinically obtained data have shown that acute kidney injury (AKI) is linked to accelerated chronic kidney disease (CKD) progression.
Anderson, Amanda H +21 more
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Dealing with elements of medical encounters: An approach based on ontological realism [PDF]
, 2016 Electronic health records (EHRs) serve as repositories of documented data collected in a health care encounter. An EHR records information about who receives, who provides the health care and about the place where the encounter happens.
Fernanda, Farinelli +3 more
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