Results 21 to 30 of about 901,770 (288)

Clinical and Financial Impact of Rapid Antimicrobial Susceptibility Testing in Blood Cultures

Antibiotics, 2022
The rapid identification of pathogens that cause bloodstream infections plays a vital role in the modern clinical microbiology laboratory. Despite demonstrating a significant reduction in turnaround time and a significant effect on clinical decisions ...
Felix Roth, Nathan D. Leedahl, David D. Leedahl, Dubert M. Guerrero   +3 more
doaj   +1 more source

Prospect for HRE-free high coercivity Nd-Fe-B permanent magnets

Scripta Materialia, 2018
Recent state-of-the-art microstructure investigations on Nd-Fe-B sintered magnets have revealed that the Nd2Fe14B grains in conventional sintered magnets are exchange-coupled through ferromagnetic grain boundary phase and the coercivity is governed by ...
K. Hono, H. Sepehri‐Amin
semanticscholar   +1 more source

In situ trace element and Sm-Nd isotope analysis of accessory minerals in an Eoarchean tonalitic gneiss from Greenland: Implications for Hf and Nd isotope decoupling in Earth's ancient rocks

Chemical Geology, 2019
Some of the Earth's oldest preserved continental crustal rocks, from southern West Greenland, contain contradictory radiogenic isotope signatures, whereby Hf isotope ratios are chondritic but Nd isotope ratios are distinctly super-chondritic.
J. Hammerli, A. Kemp, M. Whitehouse
semanticscholar   +1 more source

In vitro antibacterial activity of ZnO and Nd doped ZnO nanoparticles against ESBL producing Escherichia coli and Klebsiella pneumoniae

Scientific Reports, 2016
Pure ZnO and Neodymium (Nd) doped ZnO nanoparticles (NPs) were synthesized by the co-precipitation method. The synthesized nanoparticles retained the wurtzite hexagonal structure. From FESEM studies, ZnO and Nd doped ZnO NPs showed nanorod and nanoflower
A. Hameed, C. Karthikeyan, A. P. Ahamed, N. Thajuddin, N. Alharbi, S. Alharbi, G. Ravi   +6 more
semanticscholar   +1 more source

Evaluating the Association of Face Covering Mandates on COVID-19 Severity by State

Journal of Primary Care & Community Health, 2022
Objective: During the COVID-19 pandemic in the United States, mitigation measures were implemented on a state-by-state basis. Governors were responsible for establishing interventions appropriate for their states and the timing of implementation.
Mark A. Strand, Omobosinuola Shyllon, Adam Hohman, Rick J. Jansen, Savita Sidhu, Stephen McDonough   +5 more
doaj   +1 more source

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats

Proceedings of the National Academy of Sciences of the United States of America, 2016
Significance Using structure-based drug design, we have identified a series of potent allosteric protein–protein interaction acetyl-CoA carboxylase inhibitors, exemplified by ND-630, that interact within the acetyl-CoA carboxylase subunit phosphopeptide ...
G. Harriman, J. Greenwood, Sathesh Bhat, Xinyi Huang, Ruiying Wang, D. Paul, L. Tong, A. Saha, W. Westlin, R. Kapeller, H. J. Harwood   +10 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Treating Type 2 Diabetes: A Cross-sectional Audit of Naturopathic Standards of Care Using the Naturopathic Patient Database

Journal of Evidence-Based Complementary & Alternative Medicine, 2012
The Naturopathic Patient Database is a data management tool developed by the Canadian College of Naturopathic Medicine to collect patient data from its teaching clinic, the Robert Schad Naturopathic Clinic.
Christopher Habib ND, Matthew Gowan ND, Stefan Podgrabinski, Tom Grodski ND, Brenda Leung ND, Maria Shapoval ND, Dugald Seely MSc, Kieran Cooley ND   +7 more
doaj   +1 more source