Results 11 to 20 of about 1,077 (185)

Neandertal introgression partitions the genetic landscape of neuropsychiatric disorders and associated behavioral phenotypes [PDF]

Translational Psychiatry, 2022
Despite advances in identifying the genetic basis of psychiatric and neurological disorders, fundamental questions about their evolutionary origins remain elusive.
Michael Dannemann, Yuri Milaneschi, Danat Yermakovich, Victoria Stiglbauer, Hanna Maria Kariis, Kristi Krebs, Manuel A. Friese, Christian Otte, Estonian Biobank Research Team, Kelli Lehto, Brenda W. J. H. Penninx, Janet Kelso, Stefan M. Gold   +12 more
doaj   +2 more sources

Exploring the Neandertal legacy of pancreatic ductal adenocarcinoma risk in Eurasians [PDF]

Biological Research, 2023
Background The genomes of present-day non-Africans are composed of 1–3% of Neandertal-derived DNA as a consequence of admixture events between Neandertals and anatomically modern humans about 50–60 thousand years ago.
Margherita Piccardi, Manuel Gentiluomo, Stefania Bertoncini, Raffaele Pezzilli, Bálint Erőss, Stefania Bunduc, Faik G. Uzunoglu, Renata Talar-Wojnarowska, Tomas Vanagas, Cosimo Sperti, Martin Oliverius, Mateus Nóbrega Aoki, Stefano Ermini, Tamás Hussein, Ugo Boggi, Krzysztof Jamroziak, Evaristo Maiello, Luca Morelli, Ludmila Vodickova, Gregorio Di Franco, Stefano Landi, Andrea Szentesi, Martin Lovecek, Marta Puzzono, Francesca Tavano, Hanneke W. M. van Laarhoven, Alessandro Zerbi, Beatrice Mohelnikova-Duchonova, Hannah Stocker, Eithne Costello, Gabriele Capurso, Laura Ginocchi, Rita T. Lawlor, Giuseppe Vanella, Francesca Bazzocchi, Jakob R. Izbicki, Anna Latiano, Bas Bueno-de-Mesquita, Ruggero Ponz de Leon Pisani, Ben Schöttker, Pavel Soucek, Péter Hegyi, Maria Gazouli, Thilo Hackert, Juozas Kupcinskas, Lina Poskiene, Matteo Tacelli, Susanne Roth, Silvia Carrara, Francesco Perri, Viktor Hlavac, George E. Theodoropoulos, Olivier R. Busch, Andrea Mambrini, Casper H. J. van Eijck, Paolo Arcidiacono, Aldo Scarpa, Claudio Pasquali, Daniela Basso, Maurizio Lucchesi, Anna Caterina Milanetto, John P. Neoptolemos, Giulia Martina Cavestro, Dainius Janciauskas, Xuechen Chen, Roger Chammas, Mara Goetz, Hermann Brenner, Livia Archibugi, Michael Dannemann, Federico Canzian, Sergio Tofanelli, Daniele Campa   +72 more
doaj   +2 more sources

Midfacial Morphology and Neandertal–Modern Human Interbreeding [PDF]

Biology, 2022
Ancient DNA from, Neandertal and modern human fossils, and comparative morphological analyses of them, reveal a complex history of interbreeding between these lineages and the introgression of Neandertal genes into modern human genomes.
Steven E. Churchill, Kamryn Keys, Ann H. Ross   +2 more
doaj   +2 more sources

Muscle AMP deaminase activity was lower in Neandertals than in modern humans [PDF]

Nature Communications
The enzyme AMPD1 is expressed in skeletal muscle and is involved in ATP production. All available Neandertal genomes carry a lysine-to-isoleucine substitution at position 287 in AMPD1.
Dominik Macak, Shin-Yu Lee, Tomas Nyman, Henry Ampah-Korsah, Emilia Strandback, Svante Pääbo, Hugo Zeberg   +6 more
doaj   +2 more sources

Successful surgical separation of asymmetrical caudal duplication or parasitic twinning in a kitten [PDF]

Journal of Feline Medicine and Surgery Open Reports
Case summary A female kitten with two ectopic supernumerary pelvic limbs arising from the umbilicus was born in our clinic. Five weeks after the kitten’s birth, she showed an acute deterioration in condition, with clinical signs of an ileus in the ...
Rachel Botsoglou, Rebecca Albert, Maximiljan Krauß   +2 more
doaj   +2 more sources

Highly selective cannibalism in the Late Pleistocene of Northern Europe reveals Neandertals were targeted prey [PDF]

Scientific Reports
The Troisième caverne of Goyet has yielded the largest assemblage of Neandertal remains in Northern Europe with clear evidence of anthropogenic modifications.
Quentin Cosnefroy, Isabelle Crevecoeur, Patrick Semal, Mateja Hajdinjak, Alba Bossoms Mesa, Johannes Krause, Guido Alberto Gnecchi-Ruscone, Cosimo Posth, Hervé Bocherens, Thibaut Devièse, Hélène Rougier   +10 more
doaj   +2 more sources

Evolutionary Origin of Ocular Melanoma: Associations With rs12913832 G Allele Frequency and Latitude. [PDF]

Cancer Med
The rs12913832 derived (G) allele frequency (blue‐eye allele) was a markedly stronger predictor of ocular melanoma incidence than geographic latitude, with approximately 92% of the latitude effect mediated through allele frequency. These findings indicate that pigmentation‐related genetic variation contributes substantially to global differences in ...
Witzenhausen H, Helgadottir H, Höiom V, Olofsson Bagge R, Stålhammar G.   +4 more
europepmc   +2 more sources

Long-range regulatory effects of Neandertal DNA in modern humans [PDF]

Genetics, 2023
Danat Yermakovich, Vasili Pankratov, Urmo Vosa   +2 more
exaly   +2 more sources

Artekale 6 (Plentzia, Bizkaia). Un nuevo asentamiento al aire libre de corta duración del Paleolítico Medio en Uribe Kosta [PDF]

Munibe Antropologia-Arkeologia, 2022
En el transcurso de una intervención arqueológica en el solar nº 6 de la calle Artekale 6 de la villa de Plentzia (Bizkaia) se localizó un conjunto lítico sobre el sustrato rocoso y bajo un depósito de arcillas de 40 cm de espesor.
Joseba Rios-Garaizar, José Ángel Lecanda, Ander Ortega   +2 more
doaj   +1 more source

Neandertals revised [PDF]

Proceedings of the National Academy of Sciences, 2016
The last decade has seen a significant growth of our knowledge of the Neandertals, a population of Pleistocene hunter-gatherers who lived in (western) Eurasia between ∼400,000 and 40,000 y ago. Starting from a source population deep in the Middle Pleistocene, the hundreds of thousands of years of relative separation between African and Eurasian groups ...
Roebroeks, W., Soressi, M.A.
openaire   +3 more sources