Results 121 to 130 of about 4,318,169 (286)
The Astrophysical JournalWe investigate various short-warning mitigation scenarios via fragmentation for a hypothetical impact of asteroid 2023 NT1, a near-Earth object (NEO) that was discovered on 2023 July 15, two days after its closest approach to Earth on July 13.
Brin Bailey +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
The Astronomical JournalAsteroids offer valuable insights into the formation and evolution of the solar system. Understanding their rotation and shape is essential for studying asteroid collision histories and geological processes, as well as for planning exploration missions ...
Yi Liu, Bo Wu, Hongliang Li
doaj +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Surface Heterogeneity, Physical, and Shape Model of Near-Earth Asteroid (52768) 1998 OR2
The Planetary Science JournalOn 2020 April 29, the near-Earth object (52768) 1998 OR2 experienced a close approach to Earth at a distance of 16.4 lunar distances (LD). 1998 OR2 is a potentially hazardous asteroid of absolute magnitude H = 16.04 that can currently come as close to ...
Maxime Devogèle +39 more
doaj +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
JWST Characterization of Earth Quasi-satellite (469219) Kamo‘oalewa
The Astrophysical Journal LettersNear-Earth asteroid (469219) Kamo‘oalewa is a uniquely stable quasi-satellite of the Earth and a target of the Tianwen-2 spacecraft mission. Here we report observations taken with JWST’s NIRSpec instrument in integral field unit (IFU) mode in 2026 ...
Benjamin N. L. Sharkey +7 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
The Astrophysical Journal Letters(469219) Kamo‘oalewa is the most stable Earth quasi-satellite and the target of China’s Tianwen-2 asteroid sample return mission. Due to its small size, fast rotation, and the limited observing geometry accessible from the ground, many physical ...
Xiaoyu Sun +10 more
doaj +1 more source