Results 61 to 70 of about 3,570,160 (355)

Spectral-element simulations of long-term fault slip: Effect of low-rigidity layers on earthquake-cycle dynamics [PDF]

open access: yes, 2011
We develop a spectral element method for the simulation of long-term histories of spontaneous seismic and aseismic slip on faults subjected to tectonic loading.
Ampuero, J.-P., Kaneko, Y., Lapusta, N.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Impact of Near-Fault Seismic Inputs on Building Performance: A Case Study Informed by the 2023 Maras Earthquakes

open access: yesApplied Sciences
This study investigates the seismic performance of existing reinforced concrete (RC) buildings, focusing on the influence of near-fault ground motions caused by proximity to fault lines.
Mehdi Öztürk, Mehmet Ali Karan
doaj   +1 more source

Ambient Vibration Based Model Updating Effects on the Earthquake Response of Tall Buildings [PDF]

open access: yes, 2016
The study investigates ambient vibration based model updating effects on the seismic behaviour of a RC tall building subjected to far and near-fault ground motions. A 17-storey building built in Giresun, Turkey is selected as an application.
Bayraktar, Alemdar   +2 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Comparison between the Effects of Near- and Far-Fault Ground Motions on the Seismic Response of a Soil-Pile-Structure System [PDF]

open access: yesJournal of Structural and Construction Engineering, 2016
Ground motions recorded in near-fault sites, where the rupture propagates toward the site, are significantly different from those observed in far-fault regions.
Saeed Abbasi Karafshani   +2 more
doaj  

Effect of near-fault ground motion with pulse signal on dynamic response of dam-reservoir-foundation systems

open access: yesGrađevinar, 2023
This paper aimed to determine the effects of a pulse signal of near-fault ground motion on the dynamic response of gravity dams, including dam-reservoir-foundation interaction, using different reservoir modelling approaches such as Westergaard, Lagrange,
Ahmet Can Altunisik   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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