Results 51 to 60 of about 10,023,443 (259)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Pushing the limits of deep-ultraviolet scanning near-field optical microscopy

APL Photonics, 2019
Deep-ultraviolet (DUV) microscopy and microspectroscopy have received much attention in label-free live-cell imaging, selective molecular analysis, and optical characterizations of ultrawide bandgap materials.
Ryota Ishii, Mitsuru Funato, Yoichi Kawakami   +2 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Improvement of spatial resolution by tilt correction in near-field scanning microwave microscopy

AIP Advances, 2021
The limitation of mechanical manufacturing will result in a small tilt angle of the sample stage in the horizontal direction, which decreases the spatial resolution of imaging in near-field scanning microwave microscopy (NSMM). In this paper, we focus on
Xianfeng Zhang, Zhe Wu, Quansong Lan, Zhiliao Du, Quanxin Zhou, Ruirui Jiang, Jianlong Liu, Yubin Gong, Baoqing Zeng   +8 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Near-Field Scanning Optical Microscopy [PDF]

, 2020
This paper summarizes the basics of near-field scanning microscopy, one of the most advanced methods for studying surface properties. The principles of operation of the near-field optical microscope, the most widely used in scientific researches.
Shatayev, Medet, Dukenbayev, Kanat
core   +1 more source

In situ plant materials hyperspectral imaging by multimodal scattering near-field optical microscopy

Communications Materials, 2021
Plant cells are elaborate three-dimensional polymer nano-constructs with complex chemistry. Here, multimodal scattering nearfield optical microscopy of poplar trees is used to establish in situ high-resolution mappings of the local dielectric functions ...
Anne M. Charrier, Aubin C. Normand, Ali Passian, Philip Schaefer, Aude L. Lereu   +4 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Infrared scanning near-field optical microscopy investigates order and clusters in model membranes

Due to its surface sensitivity and high spatial resolution, scanning near-field optical microscopy (SNOM) has a significant potential to study the lateral organization of membrane domains and clusters.
Generosi, J., Piston, D. W., Tolk, N. H., Margaritondo, G., Sanghera, J. S., Cricenti, A., Aggarwal, I. D., Castellano, A. Congiu   +7 more
core   +1 more source

A Novel 3D Probe for Near-Field Scanning Microwave Microscopy

Sensors
Near-field scanning microwave microscopy (NSMM) offers the ability to probe local electromagnetic properties beyond the classical Abbe diffraction limit, but achieving high resolution over practical scan areas remains challenging.
Ali M. Almuhlafi, Omar M. Ramahi
doaj   +1 more source