Results 71 to 80 of about 10,023,443 (259)

Near field optical microscopy in aqueous solution : implementation and characterization of a vibrating probe

open access: yes, 2002
Near field optical microscopy (NSOM) is one of the possible solutions to circumvent the diffraction limit, but the control of the optical probe in solution has been a technical challenge for practical applications.
Iwamoto, H,   +3 more
core   +1 more source

Scattering-type scanning near-field optical microscopy with low-repetition-rate pulsed light source through phase-domain sampling

open access: yesNature Communications, 2016
Low repetition rate lasers are suitable for studying nonlinear optical phenomena, while near-field microscopy allows high spatial resolution for nanomaterial characterisation. Here, Wang et al.
Haomin Wang, Le Wang, Xiaoji G. Xu
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Optically induced forces in scanning probe microscopy

open access: yesNanophotonics, 2014
Typical measurements of light in the near-field utilize a photodetector such as a photomultiplier tube or a photodiode, which is placed remotely from the region under test.
Kohlgraf-Owens Dana C.   +4 more
doaj   +1 more source

Improved Point Dipole Model for Subwavelength Resolution Scattering Near-Field Optical Microscopy (SNOM)

open access: yesInternational Journal of Antennas and Propagation, 2020
High-resolution microscopy technique is of significant importance for studying nanomaterials. It is necessary to understand the near-field interaction between the probe and substrate materials in order to get the fine structure of the nanomaterial in the
Guizhen Lu   +4 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Tunable-Focusing of Surface Plasmon Polaritons With a Slightly Irregular Line of Nanofootprints

open access: yesIEEE Photonics Journal, 2018
Tunable surface plasmon polariton launchers are highly demanded in various applications of nanophotonics for achieving controllable plasmonic signals coupling and multiplexing. Here, a tunable-focusing device with simplified structure is suggested.
Mingqian Zhang, Lin Sun, Jia Wang
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Scanning Probe Microscopy as a Tool for Investigation of Biomaterials

open access: yesAdvances in Electrical and Electronic Engineering, 2012
Super-microscopic techniques like scanning tunnelling microscopy, atomic force microscopy or scanning near-field optical microscopy allows investigate micro- and/or nano-scale surfaces and structures.
Veronika Novotna   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy