Results 31 to 40 of about 2,873,486 (299)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Highly luminescent colloidal CdS quantum dots with efficient near-infrared electroluminescence in light-emitting diodes [PDF]

, 2016
We acknowledge financial support from FP7 project “Laser Induced Synthesis of Polymeric Nanocomposite Materials and Development of Micro-Patterned Hybrid Light Emitting Diodes (LED) and Transistors (LET)”-LAMP (Project G.A.247928). A.K.B.
Zhang, S., LANZI, MASSIMILIANO, Samuel, I. D. W., Antolini, F, Lanzi, M, Samuel, Ifor David William, Bansal, Ashu Kumar, Orlotani, L, Serra, E., Bansal, A. K., ANTOLINI, FRANCESCO, Serra, E, STROEA, LENUTA, Allard, S, Stroea, L, ORTOLANI, LUCA, Scherf, U, Zhang, Shuyu, Scherf, U., Allard, S.   +19 more
core   +1 more source

Near-infrared photoimmunotherapy for osteosarcoma targeting epidermal growth factor receptor

Translational Oncology
Osteosarcoma is the most common bone tumor, and it possesses high metastatic propensity. Although systemic chemotherapy has improved its prognosis, improvements in survival rates have stalled in recent years.
Motofumi Suzuki, Hisataka Kobayashi, Hirofumi Hanaoka   +2 more
doaj   +1 more source

Watermelon ripeness detector using near infrared spectroscopy

Jurnal Teknologi dan Sistem Komputer, 2020
This study aimed to design and develop a watermelon ripeness detector using Near-Infrared Spectroscopy (NIRS). The research problem being solved in this study is developing a prototype wherein the watermelon ripeness can be detected without the need to ...
Edwin R. Arboleda, Kimberly M. Parazo, Christle M. Pareja   +2 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Elimination of radiation‐induced senescent cancer cells and stromal cells in vitro by near‐infrared photoimmunotherapy

Cancer Medicine
Introduction Therapy‐induced senescent cancer and stromal cells secrete cytokines and growth factors to promote tumor progression. Therefore, senescent cells may be novel targets for tumor treatment. Near‐infrared photoimmunotherapy (NIR‐PIT) is a highly
Motofumi Suzuki, Hisataka Kobayashi, Daiki Hara, Hirofumi Hanaoka   +3 more
doaj   +1 more source

Alpha Particle Emitter Radiolabeled Antibodies in Cancer Therapy: Current Status, Challenges, and Future Prospects

Pharmaceuticals
The utilization of antibodies to target radionuclides, known as radioimmunotherapy (RIT), has been actively researched for nearly five decades. Numerous significant preclinical and clinical studies in cancer therapy have been highlighted. Among them, RIT
Citra R. A. P. Palangka, Isa Mahendra, Rien Ritawidya, Naoya Kondo, Takahito Nakajima   +4 more
doaj   +1 more source

Sensores ópticos com detecção no infravermelho próximo e médio Near and mid infrared optical sensors

Química Nova, 2009
Optical chemical sensors with detection in the near and mid infrared region are reviewed. Fundamental concepts of infrared spectroscopy and optical chemical sensors are briefly described, before presenting some aspects on optical chemical sensors, such ...
Kássio M. G. Lima, Ivo M. Raimundo Jr., Andréa Monteiro S. Silva, Maria Fernanda Pimentel   +3 more
doaj   +1 more source

Speeded near infrared spectroscopy (NIRS) response detection. [PDF]

PLoS ONE, 2010
The hemodynamic response measured by Near Infrared Spectroscopy (NIRS) is temporally delayed from the onset of the underlying neural activity. As a consequence, NIRS based brain-computer-interfaces (BCIs) and neurofeedback learning systems, may have a ...
Xu Cui, Signe Bray, Allan L Reiss
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source