Results 41 to 50 of about 652,820 (300)

Arching in concrete slabs strengthened with near surface mounted fibre reinforced polymers [PDF]

Engineering Structures, 2019
Abstract This paper outlines basalt fibre reinforced polymer (BFRP) and carbon fibre reinforced polymer (CFRP) strengthening of laterally restrained concrete floor slabs. In-plane restraint has previously been shown to enhance slab capacity due to the development of internal compressive membrane action (CMA), which is not generally included in ...
Martin, Anthony, Taylor, Susan, Robinson, Desmond, Cleland, David   +3 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Development of cart-mounted pulsed radar imaging platform for near-surface geophysical surveys [PDF]

AIP Advances
This paper presents a cart-mounted pulsed radar imaging system designed for near-surface sensing in cluttered environments. The platform integrates antipodal Vivaldi antennas, a multi-channel transceiver, and a portable hardware design to enable mobile ...
Doojin Lee
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Serviceability limit state of two-way reinforced concrete slab strengthened with different techniques

MATEC Web of Conferences, 2018
The experimental results for service load of sixteen simply supported two way reinforced concrete slabs under the action of concentrated patch load were determined based on the amount of permissible deflections and the crack widths.All the slabs had the ...
Sayhood Eyad, Ali Ammar, Sharhan Zahraa
doaj   +1 more source

Flexural Capacity Prediction of RC Beams Strengthened in Terms of NSM System Using Soft Computing [PDF]

Journal of Soft Computing in Civil Engineering
In recent years, there has been a notable increase in the application of near-surface mounted fiber-reinforced polymer (FRP) reinforcement in reinforced concrete structures.
Amin Raeisi, Mohammad Kazem Sharbatdar, Hosein Naderpour, Pouyan Fakharian   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Parametric investigation of flexural performance of concrete prisms retrofitted with near-surface mounted FRP bars

Composites Part C: Open Access, 2023
This study investigates the impact of flexural retrofitting on the load-bearing capacity, ductility and failure modes of concrete prisms using the NSM-FRP technique, considering four design parameters.
Mohammad Al-Zu'bi, Mizi Fan, Lorna Anguilano   +2 more
doaj   +1 more source