Results 71 to 80 of about 1,231,300 (341)

Strengthening Effect of Prestressed Near-Surface-Mounted CFRP Tendon on Reinforced Concrete Beam

open access: yesAdvances in Materials Science and Engineering, 2018
Efforts are being made to use FRP (fiber-reinforced polymer) for reinforcements instead of traditional construction materials like steel owing to its remarkable mechanical properties.
Woo-Tai Jung   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Response of Reinforced Concrete Tapered Beams Strengthened Using NSM-CFRP Laminates

open access: yesTikrit Journal of Engineering Sciences, 2022
The present study is about an experimental investigation of the strength and response of reinforced concrete tapered beams strengthened by near surface mounting (NSM)-CFRP technique.
Saba S. H. AlAli   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Experimental study on strengthening of RC beams with Side Near Surface Mounted technique-CFRP bars

open access: yes, 2020
This paper presents an experimental program that was carried out for the purpose of studying the global flexural performance of reinforced concrete beams strengthened internally with Carbon Fiber Reinforced Polymer (CFRP) rods using the Side Near Surface
M. Abdallah   +4 more
semanticscholar   +1 more source

Miniature modular microwave end-to-end receiver [PDF]

open access: yes, 1993
An end-to-end microwave receiver system contained in a single miniature hybrid package mounted on a single heatsink is presented. It includes an input end connected to a microwave receiver antenna and an output end which produces a digital count ...
Cooley, Thomas W.   +3 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Near surface mounted CFRP-based technique for the strengthening of concrete structures [PDF]

open access: yes, 2004
To assess the effectiveness of the Near Surface Mounted (NSM) strengthening technique, an experimental program was carried out involving reinforced concrete (RC) columns and beams. In columns failing in bending the present work shows that the failure
Barros, Joaquim A. O.   +4 more
core   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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