Nebivolol Ameliorates Nitric Oxide–Deficient Hypertension [PDF]
The Scientific World Journal, 2002 Nebivolol is a new selective beta 1-adrenoceptor antagonist with nitric oxide (NO)–releasing properties. In the present study we have analyzed whether nebivolol affects the development of the arterial hypertension that follows the chronic inhibition of ...
L.A. Fortepiani +3 more
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Analytical methods for nebivolol quantification in pharmaceutical formulations and biological matrices: a comprehensive review [PDF]
Discover ChemistryNebivolol, a beta-blocker commonly prescribed for the treatment of hypertension and heart failure, functions by decelerating heart rate and promoting vasodilation, thereby enhancing blood flow and reducing blood pressure.
Kurdo A. Abdullah +4 more
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Protective effect of nebivolol on rat ovary exposed to deltamethrin toxicity [PDF]
Acta Cirúrgica Brasileira, 2023 Purpose: We aimed to investigate the antioxidant activity of nebivolol against possible damage to the ovarian tissue due to the application of deltamethrin as a toxic agent, by evaluating histopathological proliferating cell nuclear antigen (PCNA) and ...
Serap Otçu +4 more
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Differential effects of β-blockers nebivolol and metoprolol on mitochondrial biogenesis and antioxidant defense in angiotensin II-induced pathology in H9c2 cardiomyoblasts [PDF]
BMC Pharmacology and ToxicologyBackground Mitochondrial dysfunction and oxidative stress induced by overactivation of angiotensin II (Ang II) are major contributors to the progression of cardiovascular diseases (CVD).
Rukhsana Gul +3 more
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Nebivolol induced hyperkalemia: case report
Acta Clinica Croatica, 2016 In this article, we document a conclusive case of nebivolol-induced hyperkalemia for the first time in the known medical literature. Hyperkalemia is associated with serious conditions such as cardiac arrhythmias and sudden cardiac death.
Karmela Altabas +2 more
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Current Issues in Molecular Biology, 2022 We have recently illustrated that nebivolol can inhibit angiotensin II (Ang II)-mediated signaling in cardiomyoblasts; however, to date, the detailed mechanism for the beneficial effects of nebivolol has not been studied.
Rukhsana Gul +2 more
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Anticonvulsant Effect of Nebivolol alone and in Combination with Phenytoin against Maximal Electroshock-Induced Seizures in Mice [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Phenytoin is widely used in treatment of generalised tonic clonic seizures but its adverse effects make its usage limited. Hence forth, there is a need for newer antiepileptics. Studies have shown antiepileptic property for nebivolol in
Anuranjani Dhamodharan +2 more
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The β-blocker Nebivolol Is a GRK/β-arrestin biased agonist. [PDF]
PLoS ONE, 2013 Nebivolol, a third generation β-adrenoceptor (β-AR) antagonist (β-blocker), causes vasodilation by inducing nitric oxide (NO) production. The mechanism via which nebivolol induces NO production remains unknown, resulting in the genesis of much of the ...
Catherine E Erickson +8 more
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Nebivolol protects against myocardial infarction injury via stimulation of beta 3-adrenergic receptors and nitric oxide signaling. [PDF]
PLoS ONE, 2014 Nebivolol, third-generation β-blocker, may activate β3-adrenergic receptor (AR), which has been emerged as a novel and potential therapeutic targets for cardiovascular diseases.
Zheng Zhang +11 more
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