Results 31 to 40 of about 2,317 (166)
Nebivolol Desensitizes Myofilaments of a Hypertrophic Cardiomyopathy Mouse Model
Background: Hypertrophic cardiomyopathy (HCM) patients often present with diastolic dysfunction and a normal to supranormal systolic function. To counteract this hypercontractility, guideline therapies advocate treatment with beta-adrenoceptor and Ca2 ...
Sabrina Stücker +7 more
doaj +1 more source
Carotid artery dissection linked to intermittent apnoeic swimming: A case–control study
Abstract Internal carotid artery (ICA) dissection is a rare and potentially devastating cause of cerebral ischaemia, initiated by an intimal tear or rupture of the vasa vasorum, that can lead to an intraluminal thrombus, vascular stenosis, occlusion, or dissecting aneurysm formation.
Damian M. Bailey +14 more
wiley +1 more source
Nebivolol-induced hepatoxicity: a case report
Nebivolol is a third-generation beta-blocker known for its high selectivity for beta-1 adrenergic receptors and its unique ability to induce vasodilation via nitric oxide (NO) release.
Lynn Srour +3 more
doaj +1 more source
Background. Elevated blood pressure (BP) in the acute phase of ischemic stroke is associated with heightened risk of early disability and death. However, whether BP-lowering in this setting is beneficial and the exact levels at which BP should be ...
Eleni Georgianou +5 more
doaj +1 more source
ABSTRACT There is increasing evidence, from cellular, animal and human epidemiological studies, linking β‐blockers with reductions in cancer growth and metastasis. Propranolol is the most investigated β‐blocker for cancer; although as many different off‐patent β‐blockers exist, there is little commercial incentive to drive comparative clinical trials ...
Jillian G. Baker
wiley +1 more source
New Data for Nebivolol after In Silico PK Study: Focus on Young Patients and Dosage Regimen [PDF]
Lara Marques, Bárbara Costa, Nuno Vale
openalex +1 more source
ABSTRACT Cognitive impairment in Sjögren's disease (SD) is typically attributed to autoimmune mechanisms or small vessel disease. However, its overlap with neurodegenerative pathology remains poorly understood. We report a 74‐year‐old woman with clinically diagnosed SD presenting with progressive memory decline.
Eliza Georgiou +6 more
wiley +1 more source
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan +6 more
wiley +1 more source
Nebivolol: a novel beta-blocker with nitric oxide-induced vasodilatation
Robert WeissAndroscoggin Cardiology Associates, Auburn, ME, USAAbstract: Nebivolol is a novel beta1-blocker with a greater degree of selectivity for beta1- adrenergic receptors than other agents in this class and a nitric oxide (NO)-potentiating ...
Robert Weiss
doaj

