Results 221 to 230 of about 5,338 (235)

Targeting of nebulin fragments to the cardiac sarcomere

Experimental Cell Research, 2007
Nebulin, a vertebrate skeletal muscle actin binding protein, plays an important role in thin filament architecture. Recently, a number of reports have indicated evidence for nebulin expression in vertebrate hearts. To investigate the ability of nebulin to interact with cardiac myofilaments, we have expressed nebulin cDNA fragments tagged with green ...
Zivile, Panaviene, Xiaodi A, Deng, Michael, Esham, Carole L, Moncman   +3 more
openaire   +2 more sources

Nebulin The Nebulous, Multifunctional Giant of Striated Muscle

Trends in Cardiovascular Medicine, 2003
Nebulin is a giant, modular sarcomeric protein and although it was discovered over 2 decades ago, it remains one of the most nebulous components of striated muscle. Previously, several groups identified nebulin as the prime candidate molecule for functioning as a "ruler" to specify the precise lengths of the actin (thin) filaments in skeletal muscle ...
Abigail S, McElhinny, Steven T, Kazmierski, Siegfried, Labeit, Carol C, Gregorio   +3 more
openaire   +2 more sources

Transcripts of the nebulin gene from Ciona heart and their implications for the evolution of nebulin family genes

Gene, 2019
Nebulin is a 770 kDa protein that is localized along the thin filaments of skeletal muscles in vertebrates. It is also present in the striated muscles of Amphioxus, an invertebrate cephalochordate that is phylogenetically close to vertebrates.
Akira, Nishikawa, Akira, Hanashima, Satoshi, Nakayama, Michio, Ogasawara, Sumiko, Kimura   +4 more
openaire   +2 more sources

Correlation Between Conformational and Binding Properties of Nebulin Repeats

Journal of Molecular Biology, 1996
Nebulin, a large protein (600 to 800 kDa) located in the thin filament of striated vertebrate muscle, is assumed to bind and stabilise F-actin. Complete sequence determination of human nebulin has only recently been accomplished showing a uniform modular structure along the whole length of the molecule.
Pfuhl M, Winder SJ, Morelli MAC, Labeit S, Pastore A   +4 more
openaire   +3 more sources

Nebulin regulation of actin filament lengths: new angles

Trends in Cell Biology, 2006
The highly organized arrays of thick and thin filaments found in striated muscles continue to be the subject of studies that yield groundbreaking concepts regarding cell motility. One example is the idea that massive, linearly extended polypeptides function as molecular rulers that set the length of polymeric filaments.
openaire   +2 more sources

Nebulin and nebulin-related proteins in striated muscle

Advances in Biophysics, 1996
R, Horowits, G, Luo, J Q, Zhang, A H, Herrera   +3 more
openaire   +2 more sources

Giant Muscle Proteins: Titin/Nebulin

2012
Peter Wagner, Frank C. Mooren, Hidde J. Haisma, Stephen H. Day, Alun G. Williams, Julius Bogomolovas, Henk Granzier, Siegfried Labeit, Mark Hargreaves, L. M. Castell, P. Newsholme, Robert M. Malina   +11 more
openaire   +2 more sources

Nebulin is not expressed in plants

Gene, 2012
openaire   +2 more sources

Nebulin

2008
openaire   +1 more source

Functional assessment of nebulin missense variants

Neuromuscular Disorders, 2015
J. Laitila, M. Marttila, V. Lehtokari, C. Wallgren-Pettersson, K. Pelin   +4 more
openaire   +1 more source