Characterization of amphioxus nebulin and its similarity to human nebulin [PDF]
Journal of Experimental Biology, 2009 SUMMARYIdentification of a large molecule in muscle is important but difficult to approach by protein chemistry. In this study we isolated nebulin cDNA from the striated muscle of amphioxus, and characterized the C-terminal regions of nebulins from other chordates.
Akira, Hanashima +2 more
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Nemaline Myopathy: A Case Report
Case Reports in Neurology, 2021 Generalized weakness in the pediatric and adolescent population is caused by many disorders that affect the neuromuscular axis. As next-generation sequencing (NGS) is becoming of high yield in replacing more invasive procedures, that is, muscle and nerve
Adnan A. Mubaraki
doaj +1 more source
Importance of proteins and mitochondrial changes as freshness indicators in fish muscle post-mortem. [PDF]
J Sci Food AgricAbstract Evaluating protein and mitochondrial alterations post‐mortem can contribute to determining correlations between fish‐processing parameters and ultimate fish muscle quality. The myofibrillar protein alteration during rigor mortis directly affects the texture of fish muscle.
Hematyar N, Policar T, Rustad T.
europepmc +2 more sources
Nebulin: Does It Measure up as a Ruler? [PDF]
Current Biology, 2006 A recent study has shown that the giant protein nebulin maintains the lengths of actin filaments in striated muscle cells. Although on the surface, nebulin looks like a molecular ruler, it may be playing a more complex role in regulating dynamics at the pointed end of actin filaments in striated muscle.
Velia M. Fowler +2 more
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cDNA Cloning of Mouse Nebulin Evidence that the Nebulin‐Coding Sequence is Highly Conserved Among Vertebrates [PDF]
European Journal of Biochemistry, 1996 Nebulin is a family of giant myofibrillar proteins with molecular masses ranging over 700–900 kDa. Using a human nebulin cDNA probe, we isolated three nebulin cDNA clones from a mouse skeletal muscle cDNA library. These three clones, labeled 8c, 7a and 4b, carry inserts of 2.0, 3.0 and 3.5 kb, respectively.
Jian Q. Zhang +4 more
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New experimental possibilities for statin myopathy diagnosing
Бюллетень сибирской медицины, 2021 Aim. To identify the relationships between structural proteins of myocytes, as well as indicators of antioxidant defense and metabolites of glycolysis against the background of using statins in animals in the experiment for clarifying the diagnosis of ...
E. V. Vinogradova +2 more
doaj +1 more source
MyoMed205 Counteracts Titin Hyperphosphorylation and the Expression of Contraction-Regulating Proteins in a Rat Model of HFpEF. [PDF]
J Cachexia Sarcopenia MuscleABSTRACT Background Heart failure with preserved ejection fraction (HFpEF) is associated with exercise intolerance, accompanied by alterations in the peripheral skeletal muscle (SKM). We have recently shown that titin, a giant sarcomere protein, is hyperphosphorylated in HFpEF.
Vahle B +11 more
europepmc +2 more sources
Effect of Lysosomal Cathepsin L on Proteolysis of Beef Myofibrillar Proteins In Vivo and In Vitro
Foods, 2022 This study investigated the effects of cathepsin L on proteolysis of beef myofibrillar proteins in vivo and in vitro. Results indicated that cathepsin L affected the degradation of desmin and troponin-T during postmortem aging, and the extent of ...
Baowei Cui +3 more
doaj +1 more source
An adult nemaline myopathy patient with respiratory and heart failure harboring a novel NEB variant
eNeurologicalSci, 2020 Nemaline myopathy is a heterogeneous disorder of skeletal muscle, and histologically characterized by the presence of nemaline bodies in muscle fibers. Patients with typical congenital form of nemaline myopathy initially present with proximal but later ...
Masahiro Ohara +7 more
doaj +1 more source
Lower Limb Radiology of Distal Myopathy due to the S60F Myotilin Mutation [PDF]
, 2009 Distal myopathies are a clinically and genetically heterogenous group of disorders in which the distal limb musculature is selectively or disproportionately affected.
Birchall, Daniel +8 more
core +1 more source