Results 51 to 60 of about 745 (121)
Current Research in Food Science, 2022 Dipeptidyl peptidase-IV (DPP-IV) inhibitory peptides from fermented foods exhibit great potential to alleviate type 2 diabetes mellitus (T2DM). In this study, the DPP-IV inhibition activity of peptide extract from Chouguiyu was obviously enhanced after 4–
Daqiao Yang +7 more
doaj +1 more source
Evolutionary Applications, Volume 19, Issue 6, June 2026.ABSTRACT Horses are major domestic animals and cultural symbols that have accompanied humans for millennia. They underpin transport, agriculture, warfare and sport, and also provide a model for studying domestication, complex traits and adaptive evolution.
Ying Lu +6 more
wiley +1 more source
Nebulin: Does It Measure up as a Ruler? [PDF]
, 2006 A recent study has shown that the giant protein nebulin maintains the lengths of actin filaments in striated muscle cells. Although on the surface, nebulin looks like a molecular ruler, it may be playing a more complex role in regulating dynamics at the ...
Fowler, Velia M. +2 more
core +1 more source
FASEB BioAdvances, Volume 8, Issue 4, April 2026.(a) C2C12 myoblasts were cultured and differentiated over 7 days until mature myotubes were formed. (b) Myotubes were treated with PEA (10 μM), IBU (100 μM) or VC for 36 h. Simultaneously, cells were incubated with D2O (deuterium oxide) for isotopic labeling.
Paige L. Cole +3 more
wiley +1 more source
Clinical Genetics, Volume 109, Issue 4, Page 772-777, April 2026.CRISPR activation of NEB in fibroblasts, followed by RNA‐sequencing, documents spliceogenic effects of a NEB intronic variant. The assay enabled variant reclassification as likely pathogenic, providing molecular diagnosis in fetuses with Arthrogryposis multiplex congenita 6.
Doriana Misceo +7 more
wiley +1 more source
Understanding the functions of titin and nebulin [PDF]
, 1992 Individual molecules of the giant muscle proteins titin and nebulin span large distances in the sarcomere. Approximately one-third of the titin molecule forms elastic filaments linking the ends of thick filaments to the Z-line.
Trinick, John, John Trinick
core +1 more source
ACTA1‐Related Adult‐Onset Scapuloperoneal Myopathy With Cores and Rods
Neuropathology and Applied Neurobiology, Volume 52, Issue 2, April 2026.We report a patient with an adult‐onset, slowly progressive, ACTA1‐related scapuloperoneal myopathy with cores and rods, determined by the heterozygous variant NM_001100.4:c.1001C > T, p.(Pro334Leu). The scapuloperoneal phenotype could represent a distinct subcategory, and the characterisation of this patient with a less severe, different clinical ...
Alexandru Caramizaru +10 more
wiley +1 more source
Deciphering the Effect of Nemaline-Myopathy Nebulin Mutations on Desmin Binding [PDF]
, 2013 Our research focuses on the role of intermediate proteins in human disease. Desmin, a major intermediate filament protein in muscle cells, is organized into a central coiledcoil alpha helical domain flanked by globular head and tail domains.
Jacobs, Krystyna M
core +1 more source
An integrated diagnosis strategy for congenital myopathies. [PDF]
PLoS ONE, 2013 Congenital myopathies are severe muscle disorders affecting adults as well as children in all populations. The diagnosis of congenital myopathies is constrained by strong clinical and genetic heterogeneity. Moreover, the majority of patients present with
Johann Böhm +18 more
doaj +1 more source
Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle +6 more
wiley +1 more source