Results 51 to 60 of about 2,672 (202)
Nemaline myopathy (NM) is one of the most common forms of congenital myopathy and it is identified by the presence of “nemaline bodies” (rods) in muscle fibers by histopathological examination.
Rocío Piñero-Pérez +12 more
doaj +1 more source
(a) C2C12 myoblasts were cultured and differentiated over 7 days until mature myotubes were formed. (b) Myotubes were treated with PEA (10 μM), IBU (100 μM) or VC for 36 h. Simultaneously, cells were incubated with D2O (deuterium oxide) for isotopic labeling.
Paige L. Cole +3 more
wiley +1 more source
Roles of Nebulin Family Members in the Heart
The members of the nebulin protein family, including nebulin, nebulette, LASP-1, LASP-2, and N-RAP, contain various numbers of nebulin repeats and bind to actin, but are otherwise heterogeneous with regard to size, expression pattern, and function. This review focuses on the roles of nebulin family members in the heart.
Bang, Marie-Louise, Chen, Ju
openaire +4 more sources
Following the publication of this paper [1], it was brought to the authors’ attention that one of the contributing authors was left off of the paper. The authors apologize for the unfortunate oversight.
Frank Li +7 more
doaj +1 more source
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle +6 more
wiley +1 more source
Structural and functional roles of nebulin in skeletal muscle [PDF]
Skeletal muscles generate force through crossbridge interactions between actin thin filaments and myosin thick filaments within sarcomeres, which are, in turn, organized into a myofibrillar lattice in muscle fibers.
Gokhin, David Samuel
core
Nemaline myopathy is a rare neuromuscular disorder that affects 1 in 50,000 live births, with prevalence as high as 1 in 20,000 in certain populations.
Boyang Qiu +4 more
doaj +1 more source
Effect of Load on Non‐Muscle Myosin 2 Paralog Filaments in a Biomimetic Contractile Actin Array
The main paralogs of non‐muscle myosin 2 are studied on a micropatterned array of anti‐parallel actin filaments. This sarcomere‐like platform reveals myosin's load‐dependent behavior, and the resulting tension is quantified using embedded FRET sensors for both myosin and anchored actin.
Philip Bleicher +8 more
wiley +1 more source
Usher syndrome and Nebulin‐associated myopathy in a single patient due to variants in MYO7A and NEB
In a patient with Usher syndrome and atypical muscle complaints, we have identified two separate variants in MYO7A andNEB genes by exome sequencing. The homozygous variants in these two recessive genes could explain the full phenotype of our patient.
Nuno Maia +8 more
doaj +1 more source
Dipeptidyl peptidase-IV (DPP-IV) inhibitory peptides from fermented foods exhibit great potential to alleviate type 2 diabetes mellitus (T2DM). In this study, the DPP-IV inhibition activity of peptide extract from Chouguiyu was obviously enhanced after 4–
Daqiao Yang +7 more
doaj +1 more source

