Results 31 to 40 of about 45,782 (293)

Aerosol Delivery of Dornase Alfa Generated by Jet and Mesh Nebulizers

Pharmaceutics, 2020
Recent reports on mesh nebulizers suggest the possibility of stable nebulization of various therapeutic protein drugs. In this study, the in vitro performance and drug stability of jet and mesh nebulizers were examined for dornase alfa and compared with ...
Kyung Hwa Chang, Sang-Hyub Moon, Sun Kook Yoo, Bong Joo Park, Ki Chang Nam   +4 more
doaj   +1 more source

Isolated reversible mydriasis was associated with the use of nebulized ipratropium bromide: a case series using quantitative pupilometer in Korea [PDF]

Acute and Critical Care
Background Abnormal pupillary reactivity is a neurological emergency requiring prompt evaluation to identify its underlying causes. Although isolated unilateral mydriasis without accompanying neurological abnormalities is rare, it has occasionally been ...
Soo-Hyun Park, Tae Jung Kim, Sang-Bae Ko
doaj   +1 more source

An empirical method to cluster objective nebulizer adherence data among adults with cystic fibrosis [PDF]

, 2017
Background: The purpose of using preventative inhaled treatments in cystic fibrosis is to improve health outcomes. Therefore, understanding the relationship between adherence to treatment and health outcome is crucial.
Campbell, M. J., Curley R, Wildman MJ, Wildman, M. J., Zhe Hoo, Michael Campbell, Hoo ZH, Hoo, Z., Martin Wildman, Campbell MJ, Rachael Curley, Curley, R.   +11 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Avaliação da eficiência da micronebulização na redução da população de íons poliatômicos contendo Ca, Cl e S em espectrometria de massa com plasma indutivamente acoplado [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 1013No Brasil, os procedimentos para a classificação dos resíduos sólidos em relação à sua ...
Salvador, Graziela
core  

Inhalation Forms of Ambroxol in the Therapy of Respiratory Tract Secretory-Evacuation Disorders in Acute Bronchitis in Children

Zdorovʹe Rebenka, 2014
The mucoactive therapy of children aged 1 to 5 years with acute bronchitis using drug Lasolvan solution for oral and inhalation use or syrup for oral use Lasolvan is highly effective and safe method for management of respiratory tract secretory ...
L.S. Ovcharenko, A.A. Vertegel, T.G. Andriyenko, N.V. Zhikhareva, I.V. Samokhin, V.Yu. Tkachenko   +5 more
doaj   +1 more source

Aerosol Characteristics and Physico-Chemical Compatibility of Combivent^® (Containing Salbutamol and Ipratropium Bromide) Mixed with Three Other Inhalants: Budesonide, Beclomethasone or N-Acetylcysteine

Pharmaceutics, 2020
Inhalation therapy with a nebulizer is widely used in chronic respiratory disease. Mixing inhalation solutions/suspensions for simultaneous inhalation is more convenient and might simplify the administration procedure.
Rui Zhang, Junhua Hu, Liangjun Deng, Sha Li, Xi Chen, Fei Liu, Shanping Wang, Khaja Shameem Mohammed Abdul, Huimin Beng, Wen Tan   +9 more
doaj   +1 more source

Improved Olfactory Deposition of Theophylline Using a Nanotech Soft Mist Nozzle Chip

Pharmaceutics, 2023
Currently, nasal administration of active pharmaceutical ingredients is most commonly performed using swirl-nozzle-based pump devices or pressurized syringes.
Madeline X. Zhang, Frank Verhoeven, Pieter Ravensbergen, Stefan Kooij, Rick Geoffrion, Daniel Bonn, Cees J. M. van Rijn   +6 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source