Results 41 to 50 of about 80,951 (354)

Effect that an educational program for cystic fibrosis patients and caregivers has on the contamination of home nebulizers

Jornal Brasileiro de Pneumologia, 2014
OBJECTIVE: To describe the pathogens found in home nebulizers and in respiratory samples of cystic fibrosis (CF) patients, and to evaluate the effect that a standardized instruction regarding cleaning and disinfection of nebulizers has on the frequency ...
Adriana Della Zuana, Doroti de Oliveira Garcia, Regina Célia Turola Passos Juliani, Luiz Vicente Ribeiro Ferreira da Silva Filho   +3 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

A Critical Review on Emerging Trends in Dry Powder Inhaler Formulation for the Treatment of Pulmonary Aspergillosis

Pharmaceutics, 2020
Pulmonary aspergillosis (PA), a pulmonary fungal infection caused by Aspergillus spp., is a concern for immunocompromised populations. Despite substantial research efforts, conventional treatments of PA using antifungal agents are associated with ...
Shen Nam Cheng, Zhi Guang Tan, Manisha Pandey, Teerapol Srichana, Mallikarjuna Rao Pichika, Bapi Gorain, Hira Choudhury   +6 more
doaj   +1 more source

Case Report: Can Inhaled Adenosine Attenuate COVID-19?

Frontiers in Pharmacology, 2021
This case report demonstrates a small repetition of the case series carried out in Italy wherein inhaled adenosine was administered to patients experiencing severe and worsening coronavirus disease-2019 (COVID-19).
Bruce D. Spiess, Michael Sitkovsky, Pierpaolo Correale, Nikolaus Gravenstein, Cynthia Garvan, Timothy E. Morey, Brenda G. Fahy, Leslie Hendeles, Thomas J. Pliura, Thomas D. Martin, Velyn Wu, Corey Astrom, Danielle S. Nelson   +12 more
doaj   +1 more source

Droplet evaporation residue indicating SARS-COV-2 survivability on surfaces

, 2020
SARS-CoV-2 survives and remains viable on surfaces for several days under different environments as reported in recent studies. However, it is unclear how the viruses survive for such a long time and why their survivability varies across different ...
He, Zilong, Hong, Jiarong, Kumar, S. Santosh, Li, Jiaqi, Shao, Siyao, Sokoloff, J. B.   +5 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Interchanging Reusable and Disposable Nebulizers Used with Home-Based Compressors May Result in Inconsistent Dosing: A Laboratory Investigation with Device Combinations Supplied to the US Healthcare Environment

Pulmonary Therapy
Introduction Reusable nebulizer–compressor combinations deliver inhaled medications for patients with chronic lung diseases. On hospital discharge, the patient may take home the disposable nebulizer that was packaged and combine it with their home ...
Judy Schloss, Dominic P. Coppolo, Jason A. Suggett, Mark W. Nagel, Jolyon P. Mitchell   +4 more
doaj   +1 more source

Effects of Driving Frequency and Voltage on the Performances of Vibrating Mesh Nebulizers

Applied Sciences, 2021
The functional components of vibrating mesh nebulizers are a piezoelectric ceramic with a mesh mounted on one side, a reservoir, and a driving circuit.
Sang-Hyub Moon, Kyung Hwa Chang, Hyun Mok Park, Bong Joo Park, Sun Kook Yoo, Ki Chang Nam   +5 more
doaj   +1 more source

Characterization of nebulized buparvaquone nanosuspensions—effect of nebulization technology [PDF]

Journal of Drug Targeting, 2005
The poorly soluble drug buparvaquone is proposed as an alternative treatment of Pneumocystis carinii pneumonia (PCP) lung infections. Physically stable nanosuspensions were formulated in order to deliver the drug at the site of infection using nebulization.
Hernandez-Trejo, N, Kayser, O, Steckel, H, Muller, RH   +3 more
openaire   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source