Results 41 to 50 of about 103,175 (399)

In Vitro Characterization of the eFlow Closed System Nebulizer with Glycopyrrolate Inhalation Solution

Journal of Aerosol Medicine, 2017
Background: Glycopyrrolate administered by a novel, investigational eFlow® Closed System (CS) nebulizer (eFlow CS) is being evaluated for the maintenance treatment of chronic obstructive pulmonary disease (COPD).
S. Pham, G. Ferguson, E. Kerwin, T. Goodin, A. Wheeler, Andrea Bauer   +5 more
semanticscholar   +1 more source

Droplet evaporation residue indicating SARS-COV-2 survivability on surfaces

, 2020
SARS-CoV-2 survives and remains viable on surfaces for several days under different environments as reported in recent studies. However, it is unclear how the viruses survive for such a long time and why their survivability varies across different ...
He, Zilong, Hong, Jiarong, Kumar, S. Santosh, Li, Jiaqi, Shao, Siyao, Sokoloff, J. B.   +5 more
core   +1 more source

Microbial Contamination of Nebulizers in Patients With Cystic Fibrosis

Turkish Archives of Pediatrics
Objective: Nebulizer contamination has potential harmful effects on the respiratory system. The aim was to investigate the contamination profile of the nebulizers in cystic fibrosis patients and evaluate the relationship between hygiene practices and ...
Cansu Yilmaz Yegit, Pinar Ergenekon, Nurcan Duman, Hakan Mursaloglu, Muruvvet Cenk, Burcu Suzer Uzunoglu, Gamze Tastan, Yasemin Gokdemir, Ela Erdem Eralp, Aysegul Karahasan Yagci, Fazilet Karakoc, Bulent Karadag   +11 more
doaj   +1 more source

Ultra-trace Cu isotope ratio measurements via multi-collector ICP-mass spectrometry using Ga as internal standard : an approach applicable to micro-samples [PDF]

, 2018
The capabilities of Cu isotope ratio measurements are often restricted by the small volumes of sample available and/or their low Cu concentration. In this work, an analytical approach was developed for performing Cu isotopic analysis via multi-collector ...
Costas Rodriguez, Marta, Lauwens, Sara, Vanhaecke, Frank   +2 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Nebulization of model hydrogel nanoparticles to macrophages at the air-liquid interface

Frontiers in Chemical Engineering, 2023
Introduction: Nanoparticle evaluation within the pulmonary airspace has increasingly important implications for human health, with growing interest from drug delivery, environmental, and toxicology fields.
Emma R. Sudduth, Emily L. Kolewe, Jodi Graf, Yinkui Yu, Joaquina Somma, Catherine A. Fromen   +5 more
doaj   +1 more source

Evaluasi Cara Penggunaan Inhaler Dan Nebulizer Pada Pasien [PDF]

, 2013
Inhaler dan nebulizer merupakan jenis sediaan farmasi dengan cara penggunaan khusus, keberhasilan terapi dipengaruhi oleh ketepatan cara penggunaannya.
, Arifah Sri Wahyuni, M.Sc., Apt, Purnamasari, Richa   +1 more
core  

The pharmacokinetics of nebulized nanocrystal budesonide suspension in healthy volunteers. [PDF]

, 2003
Nanocrystal budesonide (nanobudesonide) is a suspension for nebulization in patients with steroid-responsive pulmonary diseases such as asthma. The pharmacokinetics and safety of the product were compared to those of Pulmicort Respules.
Beussink, Don, Fitzgerald, Nancy, Greenberg, Howard E., Kraft, Walter, Quiring, John N., Steiger, Barry, Waldman, Scott A.   +6 more
core   +3 more sources