Results 71 to 80 of about 573,097 (333)

Antimicrobial susceptibility of bacteria isolated from newborns with suspected or confirmed necrotising enterocolitis [PDF]

, 2009
Aim. This audit aimed to identify which bacteria were associated with necrotising enterocolitis (NEC) and determine their antibiotic sensitivities. Methods.
A Gordon, D Isaacs, I Brook, K Chan, L Jardine, M Bell, M Cichocki, M Davies, P Beeby, S Bagci, S Newell   +10 more
core   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

Advanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang, Xu Chen, Haowei Xu, Zhiqi Zeng, Keyu Lu, Yu Mao, Qianru Lv, Hui Shi, Song Liu, Xian Shen, Chunyu Yin, Yang Yang, Yan Guo, Xingyun Wang, Rui Cheng   +14 more
wiley   +1 more source

Galilean Genesis: an alternative to inflation

, 2010
We propose a novel cosmological scenario, in which standard inflation is replaced by an expanding phase with a drastic violation of the Null Energy Condition (NEC): \dot H >> H^2.
Creminelli, Paolo, Nicolis, Alberto, Trincherini, Enrico   +2 more
core   +1 more source

Energy's and amplitudes' positivity [PDF]

, 2010
In QFT, the null energy condition (NEC) for a classical field configuration is usually associated with that configuration's stability against small perturbations, and with the sub-luminality of these.
A Adams, A Martin, A Nicolis, A Nicolis, Alberto Nicolis, Enrico Trincherini, L Vecchi, MA Luty, N Arkani-Hamed, P Creminelli, Riccardo Rattazzi, RM Wald, S Dubovsky, S Dubovsky   +13 more
core   +2 more sources

NEC-zero recommendations from scoping review of evidence to prevent and foster timely recognition of necrotizing enterocolitis

Maternal Health, Neonatology and Perinatology, 2017
BackgroundAlthough decades have focused on unraveling its etiology, necrotizing enterocolitis (NEC) remains a chief threat to the health of premature infants.
S. Gephart, C. Hanson, C. Wetzel, M. Fleiner, Erin Umberger, L. Martin, Suma Rao, A. Agrawal, Terri Marin, K. Kirmani, M. Quinn, Jenny M Quinn, Katherine M Dudding, Tanya Clay, J. Sauberan, Yael Eskenazi, C. Porter, Amy L. Msowoya, Christine Wyles, Melissa Avenado-Ruiz, Shayla Vo, K. Reber, J. Duchon   +22 more
semanticscholar   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Proposal of the pipe diagnosis method using in-plane bending vibration of cylindrical shell

Nihon Kikai Gakkai ronbunshu, 2018
In this paper, deterioration diagnosis for distribution main pipe was studied using the uniform cylindrical shell approximation and in-plane bending mode.
Soichiro TAKATA, Hirofumi INOUE, Shigeki SHINODA   +2 more
doaj   +1 more source

Reducing Viability Bias in Analysis of Gut Microbiota in Preterm Infants at Risk of NEC and Sepsis

Frontiers in Cellular and Infection Microbiology, 2017
Necrotising enterocolitis (NEC) and sepsis are serious diseases of preterm infants that can result in feeding intolerance, the need for bowel resection, impaired physiological and neurological development, and high mortality rates.
G. Young, Darren L. Smith, N. Embleton, J. Berrington, E. Schwalbe, S. Cummings, C. J. van der Gast, C. Lanyon   +7 more
semanticscholar   +1 more source

Combined analysis of microbial metagenomic and metatranscriptomic sequencing data to assess in situ physiological conditions in the premature infant gut. [PDF]

, 2020
Microbes alter their transcriptomic profiles in response to the environment. The physiological conditions experienced by a microbial community can thus be inferred using meta-transcriptomic sequencing by comparing transcription levels of specifically ...
Baker, Robyn, Banfield, Jillian F, Brown, Christopher T, Firek, Brian, Morowitz, Michael J, Olm, Matthew R, Raveh-Sadka, Tali, Sher, Ruth, Sher, Yonatan   +8 more
core   +2 more sources

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

Advanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan, Huzi Zhao, Pei Zhang, Pengfei Yu, Yunfei Ji, Gang Chen, Hongli Jin, Yanfang Liu, Jin Liu, Zhe‐Sheng Chen, Aiping Lyu, Xinmiao Liang, Yang Chen   +12 more
wiley   +1 more source