Results 51 to 60 of about 106,643 (308)
EBV NEC buds synthetic membranes. [PDF]
, 2022 (A) EBV NEC constructs used. Sequence of EBV BFLF2 1–67 are shown. (B) A diagram of the in-vitro budding assay. GUVs (red) bind NEC (purple and pink) which generates formation of membrane curvature allowing cascade blue (light blue) to enter the forming ...
Ekaterina E. Heldwein (12975804) +2 more
core +1 more source
Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy
Advanced Science, EarlyView.A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li +11 more
wiley +1 more source
Proposal of the pipe diagnosis method using in-plane bending vibration of cylindrical shell
Nihon Kikai Gakkai ronbunshu, 2018 In this paper, deterioration diagnosis for distribution main pipe was studied using the uniform cylindrical shell approximation and in-plane bending mode.
Soichiro TAKATA +2 more
doaj +1 more source
The T Cell Epitope Landscape of SARS-CoV-2 Variants of Concern
Vaccines, 2022 During the COVID-19 pandemic, several SARS-CoV-2 variants of concern (VOC) emerged, bringing with them varying degrees of health and socioeconomic burdens.
Simen Tennøe +3 more
doaj +1 more source
Advanced Science, EarlyView.GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han +16 more
wiley +1 more source
Derecho & Sociedad, 2020 En los últimos años se viene haciendo referencia a los contratos “colaborativos” en América Latina. Sin embargo, no existe un entendimiento común sobre qué significa dicho término, la discusión y desarrollo internacional que hay detrás.
Franco Regjo, Eric
doaj
Bandwidth Enhancement of Balanced Folded Loop Antenna Design for Mobile Handsets Using Genetic Algorithms [PDF]
, 2008 YesIn this paper, a simple folded loop antenna (FLA) for handsets with relatively wide- band impedance, designed and optimized using genetic algorithms (GA). The FLA dimensions were optimized and evaluated using GA in collaboration with NEC-2 source code.
Abd-Alhameed, Raed +2 more
core
Advanced Science, EarlyView.A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang +12 more
wiley +1 more source
An ant colony genetic fusion routing algorithm based on soft define network
IET Networks, EarlyView., 2022 Abstract Aiming at the problem that there are many paths in data forwarding in soft define network (SDN) network, and the optimal path is difficult to find, combined with the advantages of ant colony algorithm and Genetic algorithm (GA), a routing control strategy based on the ant colony genetic fusion algorithm is proposed.
Kaixin Zhao, Yong Wei, Yang Zhang
wiley +1 more source
Clinical and histological NEC incidence and NEC severity scores in Experiment 2. [PDF]
, 2014 (A) NEC incidence values are the sum of all clinical or histological NEC cases and expressed as percentage. Results were not significant. EA, n = 27; EG, n = 16. (B) Clinical NEC severity scores determined in the stomach (Stom), jejunum (Jej), ileum (Ile)
Barbara Stoll (631755) +10 more
core +1 more source