Results 71 to 80 of about 118,017 (304)

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

An ant colony genetic fusion routing algorithm based on soft define network

IET Networks, EarlyView., 2022
Abstract Aiming at the problem that there are many paths in data forwarding in soft define network (SDN) network, and the optimal path is difficult to find, combined with the advantages of ant colony algorithm and Genetic algorithm (GA), a routing control strategy based on the ant colony genetic fusion algorithm is proposed.
Kaixin Zhao, Yong Wei, Yang Zhang
wiley   +1 more source

Uncertainty-biased molecular dynamics for learning uniformly accurate interatomic potentials

npj Computational Materials
Efficiently creating a concise but comprehensive data set for training machine-learned interatomic potentials (MLIPs) is an under-explored problem. Active learning, which uses biased or unbiased molecular dynamics (MD) to generate candidate pools, aims ...
Viktor Zaverkin, David Holzmüller, Henrik Christiansen, Federico Errica, Francesco Alesiani, Makoto Takamoto, Mathias Niepert, Johannes Kästner   +7 more
doaj   +1 more source

EBV NEC buds synthetic membranes.

, 2022
(A) EBV NEC constructs used. Sequence of EBV BFLF2 1–67 are shown. (B) A diagram of the in-vitro budding assay. GUVs (red) bind NEC (purple and pink) which generates formation of membrane curvature allowing cascade blue (light blue) to enter the forming ...
Ekaterina E. Heldwein (12975804), Elizabeth B. Draganova (13021611), Michael K. Thorsen (13021608)   +2 more
core   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Applying machine learning to pharmacovigilance data: A proof‐of‐concept study

British Journal of Clinical Pharmacology, EarlyView.
Aim Machine learning (ML) applications in pharmacovigilance remain limited and underexplored. Using data from the French National pharmacovigilance database (FNPV), this proof‐of‐concept study aimed to assess the feasibility of using a ML algorithm—eXtreme Gradient Boosting (XGBoost)—combined with SHapley Additive exPlanations (SHAP) analysis, to ...
Romain Barus, Pauline Schiro, Jean‐Luc Faillie, Romane Freppel, Johana Béné, Claire de Canecaude, François Montastruc   +6 more
wiley   +1 more source

Wideband Delta-Sigma Radio-Over-Fiber Embedding a Sparse Nonlinear ISI Model Derived From Neural Networks

IEEE Access
This paper presents a novel sparse nonlinear intersymbol interference model (SnISIM) for delta-sigma radio-over-fiber (DS-RoF) systems, designed to address severe pulse distortion caused by narrowband bandpass filters in wideband millimeter-wave ...
Masaaki Tanio, Daisaku Ogasahara, Kazushi Muraoka   +2 more
doaj   +1 more source

Eustaquio Sánchez Salor: Nec mora nec requies. Selección de artículos [PDF]

, 2017
Es una reseña de la obra: Eustaquio Sánchez Salor: Nec mora nec requies. Selección de artículos. Cáceres, Universidad de Extremadura, 2017, 410 páginas.
Harto Trujillo, María Luisa
core  

Quercetin‐zinc coordination polymer coated CaCO3 nanoparticles potentiate radiotherapy through reprogramming tumor immunosuppression

BMEMat, EarlyView.
Synthesis of QZCaCO3‐PEG to synergistically enhance the immunogenicity of radiotherapy through concurrent Zn2+‐induced cancer cell pyroptosis and Que‐mediated hypoxia amelioration through sequentially suppressing TGF‐β secretion and ECM deposition. Abstract Radiotherapy has demonstrated broad applications in treating solid tumors, but the hostile tumor
Chunjie Wang, Hengze Ding, Yu Hao, Honglin An, Ziliang Dong, Minming Chen, Yujie Zhu, Quguang Li, Bin Huang, Liangzhu Feng   +9 more
wiley   +1 more source

Does digital cognitive behavioral therapy improve the insomnia and depression of workers to healthy levels? An open trial

BioPsychoSocial Medicine
Background Cognitive behavioral therapy for insomnia (CBT-I) has a high potential for improving insomnia and depressive symptoms; however, it is unclear whether the improvement of symptoms reaches the level of healthy people without these symptoms.
Isa Okajima, Miho Suzuki, Noriko Tanizawa, Ikuo Kajiyama, Reiko Ichikawa, Jou Akitomi   +5 more
doaj   +1 more source