Results 11 to 20 of about 4,848 (199)

The physicochemical fingerprint of Necator americanus. [PDF]

PLoS Neglected Tropical Diseases, 2017
Necator americanus, a haematophagous hookworm parasite, infects ~10% of the world's population and is considered to be a significant public health risk. Its lifecycle has distinct stages, permitting its successful transit from the skin via the lungs (L3)
Veeren M Chauhan, David J Scurr, Thomas Christie, Gary Telford, Jonathan W Aylott, David I Pritchard   +5 more
doaj   +8 more sources

Comprehensive analysis of the secreted proteome of adult Necator americanus hookworms [PDF]

PLoS Neglected Tropical Diseases, 2020
The human hookworm Necator americanus infects more than 400 million people worldwide, contributing substantially to the poverty in these regions. Adult stage N.
Mark S Pearson, Srikanth S Manda, Matt A Field   +2 more
exaly   +9 more sources

Massively Parallel Sequencing and Analysis of the Necator americanus Transcriptome

PLoS Neglected Tropical Diseases, 2010
BackgroundThe blood-feeding hookworm Necator americanus infects hundreds of millions of people worldwide. In order to elucidate fundamental molecular biological aspects of this hookworm, the transcriptome of the adult stage of Necator americanus was ...
Cinzia Cantacessi, Makedonka Mitreva, Aaron R Jex   +2 more
exaly   +8 more sources

Correction: The physicochemical fingerprint of Necator americanus. [PDF]

PLoS Neglected Tropical Diseases, 2022
[This corrects the article DOI: 10.1371/journal.pntd.0005971.].
Veeren M Chauhan, David J Scurr, Thomas Christie, Gary Telford, Jonathan W Aylott, David I Pritchard   +5 more
doaj   +4 more sources

Elevated Serum IgG4 Levels in a Young Patient with Polyserositis and Necator americanus Infection [PDF]

Case Reports in Immunology, 2018
IgG4-related disease is a fibroinflammatory systemic condition characterized by tumefactive lesions, lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells, storiform fibrosis, and elevated serum IgG4 concentrations.
Giuseppe D. Sanna, Roberto Manetti, Valentina de Filippo, Sergio Babudieri   +3 more
doaj   +3 more sources

Combined morphological and molecular approaches to the clinical diagnosis of Necator americanus infection: a case report [PDF]

Journal of Medical Case Reports
Background Hookworm infection remains of considerable importance to public health. However, because critical cases caused by hookworm infection are rarely observed in China, accurate and prompt diagnoses are difficult to achieve in clinical practice.
Xianshu Liu, Ailian Sun, Xingxing Zheng, Meng Xia, Yan Liu, Shuaiqin Huang, Xiang Wu   +6 more
doaj   +3 more sources

Genome of the human hookworm Necator americanus. [PDF]

Nat Genet, 2014
The hookworm Necator americanus is the predominant soil-transmitted human parasite. Adult worms feed on blood in the small intestine, causing iron-deficiency anemia, malnutrition, growth and development stunting in children, and severe morbidity and mortality during pregnancy in women. We report sequencing and assembly of the N.
Tang YT, Gao X, Rosa BA, Abubucker S, Hallsworth-Pepin K, Martin J, Tyagi R, Heizer E, Zhang X, Bhonagiri-Palsikar V, Minx P, Warren WC, Wang Q, Zhan B, Hotez PJ, Sternberg PW, Dougall A, Gaze ST, Mulvenna J, Sotillo J, Ranganathan S, Rabelo EM, Wilson RW, Felgner PL, Bethony J, Hawdon JM, Gasser RB, Loukas A, Mitreva M.   +28 more
europepmc   +9 more sources

Endoscopic Diagnosis of <i>Necator americanus</i> Infection Presenting With Persistent Iron-Deficiency Anemia: Usefulness of Image-Enhanced Endoscopy and Capsule Endoscopy. [PDF]

DEN Open
ABSTRACT Necator americanus infection is now rare in developed countries but remains an important cause of iron‐deficiency anemia and abdominal symptoms in individuals with relevant epidemiological backgrounds. A 59‐year‐old Filipino man with long‐standing unexplained iron‐deficiency anemia was admitted to our hospital for epigastric pain associated ...
Takebe T, Osawa S, Watanabe Y, Yamagata S, Aoyama T, Kawamura Y, Manabe A, Kisamori T, Sano M, Sugimoto K.   +9 more
europepmc   +2 more sources

Computer-aided identification of potential inhibitors against Necator americanus glutathione S-transferase 3 [PDF]

Informatics in Medicine Unlocked, 2022
Hookworm infection is caused by the blood-feeding hookworm gastrointestinal nematodes. Its harmful effects include anemia and retarded growth and are common in the tropics. A current control method involves the mass drug administration of synthetic drugs,
Samuel K. Kwofie, Seth O. Asiedu, Russell Koranteng, Emelia Quarshie, Elvis K. Tiburu, Whelton A. Miller, III, Michael B. Adinortey, Michael D. Wilson   +7 more
doaj   +2 more sources

Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, when administered as single doses.
Jennifer Keiser, Lucienne Tritten, Angelika Silbereisen, Benjamin Speich, Roberto Adelfio, Mireille Vargas   +5 more
doaj   +3 more sources