Results 31 to 40 of about 3,840 (149)

Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, when administered as single doses.
Jennifer Keiser, Lucienne Tritten, Angelika Silbereisen, Benjamin Speich, Roberto Adelfio, Mireille Vargas   +5 more
doaj   +1 more source

Vaccination With Trichuris muris Poly‐Cysteine and Histidine‐Tailed Protein p43 Protects Against Chronic Infection

Parasite Immunology, Volume 48, Issue 10, October 2026.
ABSTRACT Trichuris trichiura is one of the soil transmitted geohelminths which together currently affect approximately 25% of the global population resulting in considerable morbidity particularly in children and young adults. Recent estimates put infection by T. trichiura at approximately 513 million.
Allison J. Bancroft, Kelly S. Hayes, Laura Campbell, Seona Thompson, Christina Dold, Luke Blackwell, Christine S. Rollier, David J. Thornton, Richard K. Grencis   +8 more
wiley   +1 more source

Synthesis and Antiparasitic Activities of New Organometallic Derivatives of the Benzimidazole Anthelmintic Drugs

ChemBioChem, Volume 27, Issue 15, 14 August 2026.
Organometallic derivatization of existing drugs is a common strategy to look for new drug candidates. This work describes the derivatization of the benzimidazole anthelmintic scaffold, from the synthesis of the organometallic derivatives to the evaluation of their biological properties. It highlights a broad range of antiparasitic activities and leaves
Corentin Ludwig, Aya C. Taki, Joseph J. Byrne, Pierre Mesdom, Olivier Blacque, Cécile Häberli, Trix Zumkehr, Gonzalo Scalese, Leticia Pérez‐Díaz, Dinorah Gambino, Britta Lundström‐Stadelmann, Jennifer Keiser, Robin B. Gasser, Kevin Cariou, Gilles Gasser   +14 more
wiley   +1 more source

A REVIEW ON HOOKWORM DISEASE: HISTORICAL, VIRULENCE, IMMUNOMODULATION AND IMMUNE ESCAPE STRATEGIES [PDF]

Journal of the Egyptian Society of Parasitology
Hookworms are one of the most prevalent soil-transmitted helminths (STH) worldwide, they are ubiquitous in impoverished nations with limited resources, where polyparasitism is prevalent and vaccine cold chain logistics are complicated.
AMIRA MATAR, NOHA ABOU HUSSIEN
doaj   +1 more source

Unmasking the Hidden Culprit: Capsule Endoscopy Reveals Diffuse Hookworm Infestation as a Cause of Obscure Gastrointestinal Bleeding and Refractory Anemia—A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT A 70‐year‐old woman with transfusion‐dependent anemia and ongoing gastrointestinal bleeding had inconclusive findings on imaging, upper endoscopy, and colonoscopy. Capsule endoscopy revealed the diagnosis: diffuse hookworm infestation causing active bleeding throughout the small bowel and colon.
Samiyya Rasool Abbasi, Momina Mazhar Ali, Ramsha Habibullah Mangrio, Marrium Sultan Dar, Syeda Dua Azhar, Khabab Abbasher Hussien Mohamed Ahmed   +5 more
wiley   +1 more source

Sensitive Detection of Foodborne Parasitic Larvae Using a Sieving–qPCR Workflow: Application to Angiostrongylus cantonensis

Journal of Food Science, Volume 91, Issue 7, July 2026.
ABSTRACT Contaminated food and water represent potential infection sources of Angiostrongylus cantonensis, a parasitic nematode with significant zoonotic potential. Limited environmental surveillance may be due to the absence of simple and reliable screening methods. Different methods of A.
Jana Kačmaříková, Helena Stříbrná, Kateřina Janečková, Barbora Červená   +3 more
wiley   +1 more source

THE EXPERIMENTAL INFECTION OF NECATOR AMERICANUS (HOOK WORM) IN GOLDEN HAMSTER, MESOCRICETUS AURATUS

Iranian Journal of Public Health, 1996
Hook worm (Necator americanus) is one of the major pathogenic parasites in the north of Iran. Neonatal hamsters 1-3 days old showed a high degree of susceptibility to Necator americanus infection and the parasite reached to sexually mature stages in six ...
H. Khazan, G. Masuoud   +1 more
doaj  

Hookworm infection and anemia in adult women in rural Chiapas, Mexico Anemia e infección por Necator americanus en mujeres en Chiapas, México

Salud Pública de México, 2003
OBJECTIVE: To describe associations between anemia and hookworm (Necator americanus) infection in hospitalized women in rural Chiapas, Mexico. MATERIAL AND METHODS: We retrospectively reviewed the hospital records of 68 anemic women (defined as having a ...
Paula E. Brentlinger, Linnea Capps, Melinda Denson   +2 more
doaj  

Cutaneous Larva Migrans Presenting as Eczematous Dermatitis

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Cutaneous larva migrans (CLM) is a skin infection caused by animal hookworm larvae. Clinically, it appears as a red, itchy, winding (serpiginous) line, but early lesions can mimic eczema. We report a case of a 66‐year‐old farmer who initially presented with an eczematous lesion on the left foot, which was subsequently diagnosed as CLM ...
Mahesh Mathur, Sumit Paudel, Shilpa Maharjan, Himanshu Pathak, Sandhya Regmi, Sharad Shrestha   +5 more
wiley   +1 more source

Acquired resistance to the human hookworm Necator americanus in mice [PDF]

Parasite Immunology, 1988
Summary BALB/c mice were exposed to primary or secondary infection with the hamster‐adapted strain of Necator americanus, and the course of infection was monitored through worm recovery and immunological assays. Significantly fewer viable larvae were recovered from the skin site of reinfected mice on day 2 post‐infection, and fewer larvae resided in ...
Wells, Catherine, Behnke, Jerzy M.
openaire   +3 more sources