Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Processus occipito-vertebralis: а rare suboccipital abnormality with different clinical signs
Хирургия позвоночника, 2015 The paper presents three cases of similar pediatric bony abnormality at the craniovertebral junction accompanied by torti- collis and ischemic brain attacks. Two patients were operated on, and the outcomes are analyzed.
Aleksandr Yu. Mushkin +3 more
doaj +1 more source
Functional radical cervical dissection for differentiated thyroid cancer: the experience of a single center [PDF]
, 2018 There is ongoing debate regarding the role of neck dissection in differentiated thyroid cancer, about its usefulness in elective settings, and the increased costs regarding morbidity and operative time.
Adrian, Tulin +12 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Use of free microvascular flaps in the management of the head and neck defects [PDF]
Vojnosanitetski Pregled, 2006 Background/aim: In the field of contemporary head and neck reconstructive surgery, free vascularized tissue transfer is becoming a gold standard. The aim of this study was to review our clinical results and experience, with use of free microvascular ...
Nikolić Živorad +2 more
doaj +1 more source
Effects of Global Postural Reeducation versus Specific Therapeutic Neck Exercises on Pain, Disability, Postural Control, and Neuromuscular Efficiency in Women with Chronic Nonspecific Neck Pain: Study Protocol for a Randomized, Parallel, Clinical Trial [PDF]
, 2021 Tânia Mendes Fernandes +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Imaging of Pharyngocele: An Occupational Overuse Syndrome
Oman Medical Journal, 2020 Pharyngocele is a rare pathology of the pharynx caused by the laxity of the thyrohyoidmembrane. Only about 60 true lateral pharyngocele cases have been reported in the literature over the last 133 years.
Dillibabu Ethiraj +3 more
doaj +1 more source
Lack of evidence for central sensitization in idiopathic, non-traumatic neck pain : a systematic review [PDF]
, 2015 Background: Chronic neck pain is a common problem with a poorly understood pathophysiology. Often no underlying structural pathology can be found and radiological imaging findings are more related to age than to a patient's symptoms.
Bramer, Wichor +9 more
core +1 more source