Results 61 to 70 of about 2,721,344 (402)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

DMRG-CASPT2 study of the longitudinal static second hyperpolarizability of all-trans polyenes [PDF]

open access: yes, 2016
We have implemented internally contracted complete active space second order perturbation theory (CASPT2) with the density matrix renormalization group (DMRG) as active space solver [Y. Kurashige and T. Yanai, J. Chem. Phys.
Van Neck, Dimitri   +2 more
core   +2 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

The effects of cervical muscle fatigue on balance - A study with elite amateur rugby league players [PDF]

open access: yes, 2014
Neck muscle fatigue has been shown to alter an individual’s balance in a similar way to that reported in subjects suffering from neck pain or subjects that have suffered a neck injury.
Fagan, Michael J., Gosselin, Guy
core  

General neck condition for the limit shape of budding vesicles

open access: yes, 2017
The shape equation and linking conditions for a vesicle with two-phase domains are derived. We refine the conjecture on the general neck condition for the limit shape of a budding vesicle proposed by J\"{u}licher and Lipowsky [Phys. Rev. Lett. \textbf{70}
Du, Qiang, Tu, Z. C., Yang, Pan
core   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

The impact of Coronavirus (COVID-19) on head and neck cancer patients' care [PDF]

open access: yes, 2020
The impact of Coronavirus (COVID-19) on head and neck cancer patients ...
De Felice, Francesca   +2 more
core   +1 more source

Human papillomavirus as a driver of head and neck cancers

open access: yesBritish Journal of Cancer, 2019
The human papillomavirus (HPV) family includes more than 170 different types of virus that infect stratified epithelium. High-risk HPV is well established as the primary cause of cervical cancer, but in recent years, a clear role for this virus in other ...
M. E. Sabatini, S. Chiocca
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

A Comparison of the Stomatognathic and Neck Functions between Smokers and Non-smokers

open access: yesBezmiâlem Science
Objective: This study aimed to compare smokers’ and non-smokers’ stomatognathic and neck functions. Methods: The study included 100 smokers and 96 non-smokers who did not have any chronic diseases.
Oğuzhan METE   +4 more
doaj   +1 more source

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