This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth+10 more
wiley +1 more source
EXPERIMENTAL FAT NECROSIS: THE ACTION OF PANCREATIC TISSUE UPON SUBCUTANEOUS ADIPOSE TISSUE [PDF]
HERBERT U. WILLIAMS
openalex +1 more source
Imine Crosslinked, Injectable, and Self‐Healing Fucoidan Hydrogel with Immunomodulatory Properties
This study develops an injectable fucoidan‐based hydrogel with tunable properties for tissue engineering. By oxidizing fucoidan (OFu) to introduce aldehydes, imine crosslinks are formed with amine‐containing polymers, enabling self‐healing, injectability, and long‐term stability (≥28 days). The OFu‐gelatin hydrogel demonstrated biocompatibility, immune‐
Asma Talib Qureshi+3 more
wiley +1 more source
Effect of cinnamon oil (<i>Cinnamomum burmannii</i>) on the histological kidney of male diabetic rats (<i>Rattus norvegicus</i>). [PDF]
Budiastuti B+13 more
europepmc +1 more source
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen+7 more
wiley +1 more source
Can the interleukin TNF-α be used as a biomarker for pulp necrosis? [PDF]
Brasil da Silva CWL+5 more
europepmc +1 more source
Necrosis of a Large Portion of Nearly the Whole Thickness of the Shaft of the Femur: With Spontaneous Fracture and Very Great Shortening: Recovery with an Useful Limb [PDF]
J. Bell
openalex +1 more source
Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang+12 more
wiley +1 more source
LOCAL INJECTION OF HUMAN DENTAL PULP STEM CELLS FOR TREATMENT OF JUVENILE AVASCULAR NECROSIS OF THE FEMORAL HEAD: PRELIMINARY RESULTS IN IMMATURE PIGS. [PDF]
Angeli LRA+7 more
europepmc +1 more source