Results 31 to 40 of about 1,549,386 (358)

Identifying Genes Devoted to the Cell Death Process in the Gene Regulatory Network of Ustilago maydis

open access: yesFrontiers in Microbiology, 2021
Cell death is a process that can be divided into three morphological patterns: apoptosis, autophagy and necrosis. In fungi, cell death is induced in response to intracellular and extracellular perturbations, such as plant defense molecules, toxins and ...
Cinthia V. Soberanes-Gutiérrez   +4 more
doaj   +1 more source

Epoxyscillirosidine Induced Cytotoxicity and Ultrastructural Changes in a Rat Embryonic Cardiomyocyte (H9c2) Cell Line

open access: yesToxins, 2019
Moraea pallida Bak. (yellow tulp) poisoning is the most important cardiac glycoside-induced intoxication in ruminants in South Africa. The toxic principle, 1α, 2α-epoxyscillirosidine, is a bufadienolide. To replace the use of sentient animals in toxicity
Hamza Ibrahim Isa   +3 more
doaj   +1 more source

Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta Phacelocarpus neurymenioides

open access: yesMarine Drugs, 2019
The marine α-pyrone macrolide neurymenolide A was previously isolated from the Fijian red macroalga, Neurymenia fraxinifolia, and characterized as an antibacterial agent against antibiotic-resistant strains that also exhibited moderate cytotoxicity ...
Sofia-Eléna Motuhi   +11 more
doaj   +1 more source

Mechanisms of Action and Cell Death Associated with Clostridium perfringens Toxins

open access: yesToxins, 2018
Clostridium perfringens uses its large arsenal of protein toxins to produce histotoxic, neurologic and intestinal infections in humans and animals. The major toxins involved in diseases are alpha (CPA), beta (CPB), epsilon (ETX), iota (ITX), enterotoxin (
Mauricio A. Navarro   +2 more
doaj   +1 more source

Oral glutamine dipeptide or oral glutamine free amino acid reduces burned injury progression in rats

open access: yesBrazilian Journal of Biology, 2021
This study was carried out to evaluate the effect of Glutamine, as a dipeptide or a free amino acid form, on the progression of burn injuries in rats. Thirty male Wistar rats were burned with a comb metal plate heated in boiling water (98 °C) for three ...
E. K. U. Moriguti   +7 more
doaj   +1 more source

Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent

open access: yesNew England Journal of Medicine, 2001
Background Infliximab is a humanized antibody against tumor necrosis factor α (TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis. Approximately 147,000 patients throughout the world have received infliximab. Excess TNF-α in
J. Keane   +7 more
semanticscholar   +2 more sources

Involvement of JNK and Caspase Activation in Hoiamide A-Induced Neurotoxicity in Neocortical Neurons

open access: yesMarine Drugs, 2015
The frequent occurrence of Moorea producens (formerly Lyngbya majuscula) blooms has been associated with adverse effects on human health. Hoiamide A is a structurally unique cyclic depsipeptide isolated from an assemblage of the marine cyanobacteria M ...
Zhengyu Cao   +5 more
doaj   +1 more source

Different Types of Cell Death Induced by Enterotoxins

open access: yesToxins, 2010
The infection of bacterial organisms generally causes cell death to facilitate microbial invasion and immune escape, both of which are involved in the pathogenesis of infectious diseases.
Ming-Yuan Hong   +6 more
doaj   +1 more source

A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease

open access: yes, 1997
Background Studies in animals and an open-label trial have suggested a role for antibodies to tumor necrosis factor α, specifically chimeric monoclonal antibody cA2, in the treatment of Crohn's disease.
S. Targan   +8 more
semanticscholar   +1 more source

Skin Necrosis with Oculomotor Nerve Palsy Due to a Hyaluronic Acid Filler Injection

open access: yesArchives of Plastic Surgery, 2017
Performing rhinoplasty using filler injections, which improve facial wrinkles or soft tissues, is relatively inexpensive. However, intravascular filler injections can cause severe complications, such as skin necrosis and visual loss.
Jae Il Lee, Seok Joo Kang, Hook Sun
doaj   +1 more source

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