Results 31 to 40 of about 1,016,672 (340)

Rate-Equation Modelling and Ensemble Approach to Extraction of Parameters for Viral Infection-Induced Cell Apoptosis and Necrosis [PDF]

J. Chem. Phys. 145 (9), Article 094103, 8 pages (2016), 2016
We develop a theoretical approach that uses physiochemical kinetics modelling to describe cell population dynamics upon progression of viral infection in cell culture, which results in cell apoptosis (programmed cell death) and necrosis (direct cell death).
arxiv   +1 more source

A multiphase Cahn-Hilliard-Darcy model for tumour growth with necrosis [PDF]

Math. Models Methods Appl. Sci. 28 (2018) 525--577, 2017
We derive a Cahn-Hilliard-Darcy model to describe multiphase tumour growth taking interactions with multiple chemical species into account as well as the simultaneous occurrence of proliferating, quiescent and necrotic regions. Via a coupling of the Cahn-Hilliard-Darcy equations to a system of reaction-diffusion equations a multitude of phenomena such ...
arxiv   +1 more source

On the pathway of cellular uptake: new insight into the interaction between the cell membrane and very small nanoparticles

Beilstein Journal of Nanotechnology, 2016
For any living cell the exchange with its environment is vital. Therefore, many different kinds of cargo are able to enter cells via energy-dependent or -independent routes. Nanoparticles are no exemption. It is known that small silica nanoparticles with
Claudia Messerschmidt, Daniel Hofmann, Anja Kroeger, Katharina Landfester, Volker Mailänder, Ingo Lieberwirth   +5 more
doaj   +1 more source

Q fever outbreak in the terraced vineyards of Lavaux, Switzerland

New Microbes and New Infections, EarlyView., 2014
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini, I. Magouras, C. Chapuis‐Taillard, O. Clerc, E. Masserey, G. Peduto, O. Péter, S. Schaerrer, G. Schuepbach, G. Greub   +9 more
wiley   +1 more source

Clinical heterogeneity in a family with flail arm syndrome and review of hnRNPA1‐related spectrum

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1910-1917, December 2022., 2022
Abstract Objective Flail arm syndrome (FAS) is one of the atypical subtypes of amyotrophic lateral sclerosis (ALS). Mutations in hnRNPA1 encoding heterogeneous nuclear ribonucleoprotein (hnRNP) A1 are a rare genetic cause of ALS. Herein, marked clinical heterogeneity of FAS in a pedigree with a known hnRNPA1 variant was described to raise early ...
Xiaochen Han, Feixia Zhan, Yuxin Yao, Li Cao, Jianguo Liu, Sheng Yao   +5 more
wiley   +1 more source

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh, Rachel S. Kasper, Jessie Sanford, Chia‐Ling Phuah, Jason Hassenstab, Carlos Cruchaga   +5 more
wiley   +1 more source

A bibliometric analysis of PIN1 and cell death

Frontiers in Cell and Developmental Biology, 2022
Background: Regulation of cell death plays a key role in numerous diseases. As a proline isomerase, prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) is important for the regulation of signaling pathways.
Jia-Heng Zhang, Jia-Heng Zhang, Shi-Yu Ni, Ya-Ting Tan, Ya-Ting Tan, Jia Luo, Shu-Chao Wang   +6 more
doaj   +1 more source

ComplexWoundDB: A Database for Automatic Complex Wound Tissue Categorization [PDF]

, 2022
Complex wounds usually face partial or total loss of skin thickness, healing by secondary intention. They can be acute or chronic, figuring infections, ischemia and tissue necrosis, and association with systemic diseases. Research institutes around the globe report countless cases, ending up in a severe public health problem, for they involve human ...
arxiv   +1 more source

Tumor budding in invasive breast cancer - An indispensable budding touchstone

Indian Journal of Pathology and Microbiology, 2020
Background: Tumor budding denotes a phenomenon in which the tumor cells, singly or in small aggregates, become detached from the neoplastic glands at the invasive front of adenocarcinoma.
B N Kumarguru, Anikode S Ramaswamy, Shahanuma Shaik, Aruna Karri, Venugopal Sandeep Srinivas, B M Prashant   +5 more
doaj   +1 more source

Bifurcation analysis of a free boundary model of vascular tumor growth with a necrotic core and chemotaxis [PDF]

arXiv, 2022
A considerable number of research works has been devoted to the study of tumor models. Several biophysical factors, such as cell proliferation, apoptosis, chemotaxis, angiogenesis and necrosis, have been discovered to have an impact on the complicated biological system of tumors.
arxiv