Results 51 to 60 of about 1,073,825 (268)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Bacteremia and conventional diagnosis of Sphingobacterium spiritivorum. A case report

Medisur, 2003
This is a case report of septicaemia due to Sphingobacterium Spiritovirum that caused acute symmetric acronecrosis in a previously healthy man who received medical assistance at the University Hospital ¨Dr.
Elio Jesús Núñez Tamayo, Susana Chamero Melgarejo, Rafael Gómez Marrero, Nancy Ramírez Martínez, Eva María García Mauri, Remberto González Enoa   +5 more
doaj  

Assessment of interactions between defoliation and Phytophthora plurivora stem infections of birch seedlings

The Forestry Chronicle, 2018
Silver birch, (Betula pendula), is an important forest tree species in Poland used for afforestation in rural areas and planted in wet forest types to ameliorate excess water. Physiological stress may increase susceptibility of trees to disease and it is
Tomasz Oszako, Dzmitry Voitka, Miłosz Tkaczyk, Nenad Keča, Lassaâd Belbahri, Justyna A. Nowakowska   +5 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

COMPLICATIONS OF TERMINAL COLOSTOMY IN PATIENTS WITH TUMOROUS LARGE INTESTINE ILEUS AND THEIR SURGICAL MANAGEMENT

Вестник хирургии имени И.И. Грекова, 2016
The article analyzed the structure, incidence rate and results of surgical treatment of paracolostomal complications in 69 patients out of 134 (aged from 23 to 77 years old).
S. A. Aliev, B. M. Zeinalov, E. S. Aliev
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Melatonin in the dermal film limits the blood lymphocyte death in experimental thermal trauma

Медицинская иммунология, 2021
According to WHO data, about 11 million people need medical care after burns every year. In the overall structure of burns, the share of thermal trauma (TT) is 80%.
M. V. Osikov, E. V. Simonyan, A. A. Ageeva, Yu. I. Ageev   +3 more
doaj  

Enhanced T Cell Responses Induced by a Necrotic Dendritic Cell Vaccine, Expressing HCV NS3

Frontiers in Microbiology, 2020
A vaccine that induces potent, broad and sustained cell-mediated immunity, resulting in effective memory has the potential to restrict hepatitis C (HCV) virus infection.
Zelalem A. Mekonnen, Makutiro G. Masavuli, Wenbo Yu, Wenbo Yu, Jason Gummow, Dawn M. Whelan, Zahraa Al-Delfi, Joseph Torresi, Eric J. Gowans, Branka Grubor-Bauk   +9 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Comparative functional analyses of the movement and coat proteins of grapevine Pinot gris virus, encoded by symptomatic and asymptomatic variants

Frontiers in Plant Science
Using small RNA high-throughput sequencing (HTS), we previously demonstrated the widespread distribution of grapevine Pinot gris virus (GPGV) in Hungarian vineyards. This trichovirus has been associated with a disease known as grapevine leaf mottling and
Nikoletta Jaksa-Czotter, Emese Demián, Réka Sáray, Katalin Salánki, Éva Várallyay   +4 more
doaj   +1 more source