Results 81 to 90 of about 1,360,678 (312)
Sustain, Adapt, and Overcome—Hypoxia Associated Changes in the Progression of Lymphatic Neoplasia
Frontiers in Oncology, 2019 Irregular perfusion and related tissue hypoxia is a common feature of solid tumors the role of which in the survival and progression cancer has been gradually recognized.
Orsolya Matolay, Gábor Méhes
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
AN INTRASEASONAL BIOECONOMIC MODEL OF PLRV NET NECROSIS [PDF]
A bioeconomic model is developed as an IPM planning tool to combat PLRV net necrosis in the PNW potato industry. Environmental/biological and production processes are linked to marketing activities using discrete time control. We find that pesticides can
Folwell, Raymond J. +3 more
core
Dark reactivation of ultraviolet-irradiated tobacco necrosis virus [PDF]
, 1968 Some damage caused in tobacco necrosis virus by u.v. radiation could be repaired in darkness in Chenopodium amaranticolor (dark reactivation) but not in French bean or in tobacco.
Kleczkowski, A.
core +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Evaluating SnapshotNIR for Tissue Oxygenation Measurement Across Skin Types After Mastectomy
BioengineeringAccurate monitoring of mastectomy skin flap (MSF) perfusion is critical, especially in patients with darker skin pigmentation at higher risk of misdiagnosed tissue ischemia.
Saif Badran +6 more
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Signalling pathways involved in TNFα-induced cytoprotection : role of reactive oxygen species [PDF]
, 2005 Includes bibliographical references (leaves 73-89).Tumour necrosis factor alpha (TNFa) is a pleiotropic cytokine which has both beneficial and deleterious effects.
Lacerda, Lydia
core +1 more source