Results 81 to 90 of about 1,079,667 (268)
Frontiers in Pharmacology, 2018 Ingestion or exposure to chemicals poses a serious health risk. Early detection of cellular changes induced by such events is vital to identify appropriate countermeasures to prevent organ damage. We hypothesize that chemically induced organ injuries are
Patric Schyman +5 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Cancer Letters, 2013 Tumor necrosis factor (TNF) is a critical cytokine, which contributes to both physiological and pathological processes. This mini-review will briefly touch the history of TNF discovery, its family members and its biological and pathological functions. Then, it will focus on new findings on the molecular mechanisms of how TNF triggers activation of the ...
openaire +2 more sources
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Water Quality Parameters and Histopathological Changes in Gills and Liver of Clarias gariepinus Juveniles Exposed to Ethanol Leaf Extract of Senna occidentalis [PDF]
Journal of Stress Physiology & BiochemistryThe leaf of coffee senna or septic weed, Senna occidentalis, is among the medicinal and toxic plants whose toxicity on fish has not thoroughly been assessed.
Adesanya, Oluwatosin E. +5 more
doaj
Signalisation apototique induite par les LDL oxydées Implication dans l’athérosclérose
Oléagineux, Corps gras, Lipides, 2006 The balance between vascular cell proliferation vs apoptosis plays a key role in vessel wall remodeling. Intimal migration and proliferation of smooth muscle cells (SMC), and secretion of extracellular matrix are involved in fibrous cap formation and ...
Negre-Salvayre Anne +2 more
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
A Case of Cavitary Lung Metastasis From Prostate Cancer
Respirology Case ReportsA 79‐year‐old man was found to have multiple nodules in the lung fields on chest computed tomography. Metastatic lung cancer was suspected; however, the primary site remained elusive. After 1 year of follow‐up, both the nodules had enlarged.
Shinnosuke Ohnaka +10 more
doaj +1 more source