The Microbiota of the Extremely Preterm Infant. [PDF]
Colonization of the extremely preterm infant's gastrointestinal tract and skin begins in utero and is influenced by a variety of factors, the most important including gestational age and environmental exposures. The composition of the intestinal and skin
Sohn, Kristin, Underwood, Mark A
core +1 more source
DNA damage contributes to age‐associated differences in SARS‐CoV‐2 infection
Our data suggest DNA damage contributes to age‐associated differences in SARS‐CoV‐2 infection and provide a novel target for anti‐viral intervention. Abstract Coronavirus disease 2019 (COVID‐19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is known to disproportionately affect older individuals.
Rui Jin+14 more
wiley +1 more source
Objectives: To summarize and differentiate abdominal ultrasound findings of necrotizing enterocolitis and food protein-induced enterocolitis syndrome. Methods: From January 2017 to December 2018, the abdominal ultrasound results of 304 cases diagnosed ...
Yiyi Guo+4 more
doaj
ULTRASOUND DIAGNOSIS OF NECROTIZING ENTEROCOLITIS
The necrotizing enterocolitis remains the basic disease leading to a mortality of mainly prematurely born children with low and extremely low body weight.
M. I. Pykov+4 more
doaj +1 more source
Necrotizing enterocolitis associated with dysbiosis of preterm gut microbiome: A review [PDF]
Preterm birth is defined as any birth before 37 weeks of completed weeks of gestation. Preterm infants are said to have an imbalanced intestinal and immune system.
Abdulkadir, B.+9 more
core +2 more sources
A review of the immunomodulating components of maternal breast milk and protection against necrotizing enterocolitis [PDF]
Breast milk contains immunomodulating components that are beneficial to newborns during maturation of their immune system. Human breast milk composition is influenced by an infant\u27s gestational and chronological age, lactation stage, and the mother ...
Fiorentino+5 more
core +2 more sources
Hydrogen Sulfide Donor GYY4137 Acts Through Endothelial Nitric Oxide to Protect Intestine in Murine Models of Necrotizing Enterocolitis and Intestinal Ischemia [PDF]
BACKGROUND: Necrotizing enterocolitis (NEC) in premature infants is often a devastating surgical condition with poor outcomes. GYY4137 is a long-acting donor of hydrogen sulfide, a gasotransmitter that is protective against intestinal injury in ...
Drucker, Natalie A.+3 more
core +1 more source
Necrotizing enterocolitis in the neonatal period—morbidity, risk factors, and recommendations for prevention [PDF]
Necrotizing enterocolitis (NEC) is a highly debilitating gastrointestinal disorder distinguished by intestinal inflammation and necrosis. This specific condition is commonly acknowledged as a common gastrointestinal emergency in neonates, particularly ...
Rangelova, Vanya
core +2 more sources
Generalizability analyses with a partially nested trial design: the Necrotizing Enterocolitis Surgery Trial [PDF]
We discuss generalizability analyses under a partially nested trial design, where part of the trial is nested within a cohort of trial-eligible individuals, while the rest of the trial is not nested. This design arises, for example, when only some centers participating in a trial are able to collect data on non-randomized individuals, or when data on ...
arxiv
Necrotic tumor growth: an analytic approach [PDF]
The present paper deals with a free boundary problem modeling the growth process of necrotic multi-layer tumors. We prove the existence of flat stationary solutions and determine the linearization of our model at such an equilibrium. Finally, we compute the solutions of the stationary linearized problem and comment on bifurcation.
arxiv +1 more source