Results 71 to 80 of about 85,835,167 (297)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Jumping to delusions? Paranoia, probabilistic reasoning, and need for closure
, 2007 INTRODUCTION: The present study was designed to replicate and extend the findings of Bentall and Swarbrick (2003). It was hypothesised that patients with a history of persecutory delusions would display higher need for closure and a more extreme jumping ...
Coltheart, Max +2 more
core +1 more source
Frontiers in Psychology, 2016 According to the dual-process theoretical perspective adopted in the presented research, the efficiency of deliberative processes in decision making declines with age, but experiential processes are relatively well-preserved.
Maciej eKoscielniak +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Lane Closure Policy Development, Enforcement, and Exceptions: A Survey of Seven State Transportation Agencies, February 2007 [PDF]
, 2007 Traffic volume increases and an aging infrastructure create the need for reconstruction, rehabilitation, and maintenance of existing facilities. As more motorists feel that delays should be minimal during highway renewal projects, lane closures that ...
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Need for closure and youngsters' leisure time preferences [PDF]
, 2005 The Need for Closure is introduced as an individual characteristic that can help explain individual differences in engagement in leisure activities. Both a leisure engagement inventory and a validated Dutch version of the Need for Closure Scale were ...
Geuens, Maggie, Vermeir, Iris
core +2 more sources
Psychology of Language and CommunicationResearch on individual differences in irony understanding is not sparse, however the need for cognitive closure (NFC) has not been taken into consideration yet.
Branowska Katarzyna, Koziński Konrad
doaj +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Amplatzer device closure of an inferior venosus atrial septal defect after surgical closure of a secundum atrial septal defect [PDF]
, 2004 This article presents a patient who had transcatheter closure of a low atrial septal defect which was overlooked during surgical closure of a secundum atrial septal defect.
DeGiovanni, Joseph V. +2 more
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