Results 81 to 90 of about 85,835,167 (297)

Relationships between self-efficacy beliefs and personal factors in final-year medical students

open access: yesBMC Medical Education
Background Medical students entering postgraduate training often feel ill-prepared for clinical practice. This has implications for physician well-being and the quality of patient care.
Lea Jebram, Sigrid Harendza
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Ambiguity and uncertainty tolerance, need for cognition, and their association with stress. A study among Italian practicing physicians

open access: yesMedical Education Online, 2017
Medical practice is inherently ambiguous and uncertain. The physicians’ ability to tolerate ambiguity and uncertainty has been proved to have a great impact on clinical practice. The primary aim of the present study was to test the hypothesis that higher
Paola Iannello   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Construction of the Need for Emotional Closure Scale

open access: yes, 2020
In this study, we are interested in creating a novel scale to measure the need for emotional closure as an individual characteristic. The developed scale includes items asking for the extent to which individuals need emotional closure over past events ...
Irem Ergen, Sami Gulgoz
core   +1 more source

Search for Expectancy-inconsistent Information Reduces Uncertainty Better: The Role of Cognitive Capacity

open access: yesFrontiers in Psychology, 2016
Motivation and cognitive capacity are key factors in people’s everyday struggle with uncertainty. However, the exact nature of their interplay in various contexts still needs to be revealed.
Paweł eStrojny   +3 more
doaj   +1 more source

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