Results 121 to 130 of about 1,008,720 (296)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Understanding safety-critical interactions with a home medical device through Distributed Cognition [PDF]
, 2015 As healthcare shifts from the hospital to the home, it is becoming increasingly important to understand how patients interact with home medical devices, to inform the safe and patient-friendly design of these devices.
Blandford, AE, Mayer, A, Rajkomar, A
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Studia PsychologicaStudents constitute the primary agents in the educational process, and their individual cognitive differences coupled with emotional experiences significantly influence the efficacy of learning outcomes. This investigation encompassed 550 collegiate and
Qianguo Xiao +3 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Robots as Powerful Allies for the Study of Embodied Cognition from the Bottom Up [PDF]
A large body of compelling evidence has been accumulated demonstrating that embodiment – the agent’s physical setup, including its shape, materials, sensors and actuators – is constitutive for any form of cognition and as a consequence, models of ...
Hoffmann, Matej, Pfeifer, Rolf
core
Thinking Skills in England's National Curriculum [PDF]
, 2008 This paper sets out to explore some of the issues raised by the introduction of a number of particular skills in the English National Curriculum known collectively as thinking skills.
Glevey, Kwame
core +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
ADAPTASI BAHASA DAN BUDAYA NEED FOR COGNITION SCALE
Jurnal Sains Psikologi, 2018 Penelitian ini bertujuan untuk melakukan adaptasi need for cognition scale (NCS) (Cacioppo, dkk., 1984) untuk sampel siswa SMP di Indonesia. NCS dikembangkan untuk mengukur konstruk need for cognition yang didefinisikan sebagai kecenderungan individu ...
Ika Andrini Farida +2 more
doaj