Results 71 to 80 of about 81,661,203 (277)

Comparative cognition needs to focus more on outreach [PDF]

Finding support for the field of comparative cognition in an environment with a strong anthropocentric bent can be an uphill battle. Support may be strengthened via dissemination of findings outside typical academic channels, as they may demonstrate ...
Pinto, Carlos
core   +1 more source

Cognitive Engagement Mediates the Relationship between Positive Life Events and Positive Emotionality

Frontiers in Psychology, 2017
Need for Cognition (NFC) is conceptualized as an individuals’ tendency to engage in and enjoy effortful cognitive activity and, thus, captures one’s cognitive engagement.
Alexander Strobel, Kristin Anacker, Anja Strobel   +2 more
doaj   +1 more source

Tracing Need for Cognition in Digital Learning

Computers in Human Behavior
Need for Cognition (NFC) reflects individuals’ tendencies to engage in and enjoy effortful cognitive activities and has been linked to positive academic outcomes (e.g., higher academic achievement). However, the extent to which NFC is expressed in actual learning behaviors remains unclear.
Aki Schumacher, Luise von Keyserlingk, Hannah Deininger, Renzhe Yu, Nia Nixon, Lisa Bardach   +5 more
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Code Red: Triage, Or, COgnition-based DEsign Rules Enhancing Decisionmaking TRaining In A Game Environment [PDF]

, 2011
Serious games have a great potential for training and educating people in novel and engaging ways. However, little empirical research has been done on the effectiveness of serious games, and although early findings do point to a moderately positive ...
van der Spek, E.D., Wouters, P.J.M., Sub Cognition & Communication begr., Cognition and Communication, van Oostendorp, H.   +4 more
core  

Striving for accuracy attenuates the positive relationship between cyberbullying bystanders’ dispositional empathy and tendencies to help victims

Cyberpsychology: Journal of Psychosocial Research on Cyberpspace
Empathy is a key predictor of bystanders’ helping behaviors, yet its role in cyberbullying contexts has yielded inconsistent findings. This study investigated whether accuracy motivation, the drive to form correct and well-reasoned judgments, moderates ...
Cheng-Hong Liu, Fa-Chung Chiu, Po-Sheng Huang, Ting-Huan Lin, Chia-Lin Chang   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source