Results 91 to 100 of about 84,839,995 (240)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Journal of Theoretical and Applied Electronic Commerce ResearchGrounded in Social Impact Theory, this study examines the effects of virtual experiences generated by Mere Virtual Presence (MVP), Mere Virtual Presence with Product Experience (MVPE), and pure brand websites on consumers’ brand attitudes and purchase ...
Ching-Jui Keng +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Customization: Ideal Varieties, Product Uniqueness and Price Competition [PDF]
We study customization in the Hotelling model with two firms. In addition to providing ideal varieties, the perceived uniqueness of a customized product contributes independently to consumer utility.
Oksana Loginova, X. Henry Wang
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Some Notes on the Existence of Solution for Ordinary Differential Equations via Fixed Point Theory
Abstract and Applied Analysis, 2014 We establish a fixed point theorem with w-distance for nonlinear contractive mappings in complete metric spaces. As applications of our results, we derive the existence and uniqueness of solution for a first-order ordinary differential equation with ...
Fei He
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
A New Sufficient Condition for Uniqueness in Continuous Games [PDF]
Consider the class of games in which each player chooses a strategy from a connected subset of the real line. Many oligopoly models fall into this class.
Seamus Hogan
core
Existence and Uniqueness Theorems of Ordered Contractive Map in Banach Lattices
Abstract and Applied Analysis, 2012 This paper presents some existence and uniqueness theorems of the fixed point for ordered contractive mapping in Banach lattices. Moreover, we prove the existence of a unique solution for first-order ordinary differential equations with initial value ...
Xingchang Li, Zhihao Wang
doaj +1 more source