Results 111 to 120 of about 84,839,995 (240)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The effects of need for uniqueness and uniqueness relevant feedback on mood, recall and perceptions of peers and the self

, 1985
According to the Uniqueness theory, individuals characteristically desire to perceive themselves as moderately different from others. The effects of need for uniqueness and uniqueness relevant feedback on mood, recall, and perceptions of peers and the ...
Rosen, Sidney, Case, Thomas L.
core  

“I Know Things They Don’t Know!” The Role of Need for Uniqueness in Belief in Conspiracy Theories

, 2018
In the current research, we investigated whether belief in conspiracy theories satisfies people’s need for uniqueness. We found that the tendency to believe in conspiracy theories was associated with the feeling of possessing scarce information about the
Cécile Nurra, Anthony Lantian, Karen Douglas, Dominique Muller   +3 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Uniqueness theorem for p-biharmonic equations

Electronic Journal of Differential Equations, 2002
The goal of this paper is to prove existence and uniqueness of a solution of the initial value problem for the equation $$ (|u''|^{p-2}u'')''=lambda |u|^{q-2}u $$ where $lambdain{mathbb{R}}$ and $p,q>1$. We prove the existence for $pgeq q$ only, and give
Jiri Benedikt
doaj  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Strong uniqueness for cyclically symbiotic branching diffusions

, 2005
A uniqueness problem raised in 2001 for critical cyclically catalytic super-Brownian motions is solved in the simplified space-less case, that is, for cyclically catalytic branching diffusions .
Dawson, Donald A., Xiong, Jie, Fleischmann, Klaus   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source