Results 221 to 230 of about 4,420,455 (297)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Importance and implementation of safe nursing behaviors in nursing students' clinical practice: Importance-Performance Analysis (IPA), the borich needs assessment model, and the locus for focus model. [PDF]

PLoS One
Kim E, Kim HR.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Comprehensive Needs Assessment for Workplace Health Promotion: A Case Study of the University of Bern. [PDF]

Int J Public Health
Glauser C, Igic I, Berger T, Bertrams A, Elfering A, Engel B, Hascher T, Inauen J, Lüthi M, Nigg CR.   +9 more
europepmc   +1 more source

A behavioral health needs assessment and general psychological well-being of digital and multimedia forensic examiners. [PDF]

J Forensic Sci
Tyagi S, Seigfried-Spellar KC.
europepmc   +1 more source

Attitudes and experiences of nurses and carers with the carer support needs assessment tool intervention (CSNAT-I). [PDF]

BMC Nurs
Anker-Hansen C, Østnes SH, Torgersen K, Karlsen EB, Helgesen AK, Grøndahl VA.   +5 more
europepmc   +1 more source

Immune checkpoint inhibitors and the pediatric rheumatologist: a pediatric needs assessment. [PDF]

Pediatr Rheumatol Online J
Storwick J, Ye C, Jamal S, Maltez N, Chan M.   +4 more
europepmc   +1 more source