Results 101 to 110 of about 36,760 (309)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Negation 'presupposition' and metarepresentation: a response to Noel Burton-Roberts
, 1999 Metalinguistic negation (MN) is interesting for at least the following two reasons: (a) it is one instance of the much broader, very widespread and various phenomenon of metarepresentational use in linguistic communication, whose semantic and pragmatic ...
Carston, R
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The pragmatics of descriptive and metalinguistic negation: experimental data from French
Glossa, 2018 The phenomenon of descriptive and metalinguistic negation has been debated for a long time from a theoretical perspective. On the one hand, there are defenders of the ambiguist approach to negation, in which the descriptive negation basically serves to ...
Cristina Grisot, Joanna Blochowiak
doaj +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2012 The present essay includes six thematically connected papers on negation in the areas of the philosophy of logic, philosophical logic and metaphysics. Each of the chapters besides the first, which puts each the chapters to follow into context, highlights
De, Michael
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Negation in Pichi (Equatorial Guinea)
, 2018 This chapter provides a detailed overview of negation in Pichi, the English-lexifier Creole spoken by the people of the island of Bioko (Equatorial Guinea).
Kofi Yakpo, Yakpo, K, Yakpo, Kofi
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Negation in vernacular Brazilian Portuguese
, 2013 textAs Haegeman and Zanuttini (1996:117) discuss, when two negative elements are present in a specific syntactic domain, two possible situations may arise: "(i) the two negative elements may cancel each other out, or (ii) the two elements may ...
Martínez, Cristina, active 2003
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Modality switching and negation: ERP evidence for modality-specific simulations during negation processing [PDF]
, 2011 The Perceptual Symbol System Theory of cognition (Barsalou, 1999) suggests that modality-specific simulations underlie representation of concepts. This is evidenced by processing costs for switching modalities. That is, participants are slower to verify
Garnham, A. +4 more
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