Results 91 to 100 of about 16,277,273 (324)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Effectiveness of 23-Valent Pneumococcal Polysaccharide Vaccine Against Pneumococcal Diseases Among the Elderly Aged 60 Years or Older: A Matched Test Negative Case-Control Study in Shanghai, China [PDF]

open access: gold, 2021
Xiaodong Sun   +13 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Positives and negatives of nonsteroidal anti-inflammatory drugs in bone healing: the effects of these drugs on bone repair

open access: yesDrug Design, Development and Therapy, 2018
Barbara Lisowska,1 Dariusz Kosson,2 Karolina Domaracka3 1Department of Anesthesiology and Intensive Care, John Paul II Western Hospital, Grodzisk Mazowiecki, Poland; 2Department of Anaesthesiology and Intensive Care, Medical University of Warsaw ...
Lisowska B, Kosson D, Domaracka K
doaj  

“Tıbâk” [Tezat] Sanatı Bağlamında Kur’an’da Optimizm

open access: yesİlahiyat Tetkikleri Dergisi, 2017
Vahiy Menşeli Kutsal Metinlerin pek çok edebî sanatı bir anlatım üslûbu olarak benimsediğibilinmektedir. Bu üslûp yapılanması o metinlere efsunkâr bir ifade gücü kazandırmaktadır.Çalışma, edebî sanat türlerinden biri olan “tıbâk” [tezat] sanatı dâhilinde
Necdet Çağıl
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Counting arcs in negative curvature [PDF]

open access: yes, 2012
Let M be a complete Riemannian manifold with negative curvature, and let C_-, C_+ be two properly immersed closed convex subsets of M. We survey the asymptotic behaviour of the number of common perpendiculars of length at most s from C_- to C_+, giving ...
Parkkonen, Jouni, Paulin, Frédéric
core  

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