Results 131 to 140 of about 9,600,041 (307)

WHEN DOES NEGATIVE BRAND PUBLICITY HURT? The Moderating Influence of Analytic Versus Holistic Thinking [PDF]

open access: yes
Negative publicity can diminish positive consumer perceptions of a brand. We explore the impact of processing style on mitigating the effects of negative publicity.
Alokparna (Sonia) Basu Monga   +1 more
core  

Licensing german negative polarity items in LTAG [PDF]

open access: yes, 2008
Our paper aims at capturing the distribution of negative polarity items (NPIs) within lexicalized Tree Adjoining Grammar (LTAG). The condition under which an NPI can occur in a sentence is for it to be in the scope of a negation with no quantifiers ...
Lichte, Timm, Kallmeyer, Laura
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Development And Psychometric Properties Of Major Negative Interpersonal Events Measurement For Adolescents

open access: yesThe Journal of Studies in Language, Culture and Society
The research on finding out recent measurements/scales/inventories/questionnaires on major negative interpersonal events revealed a paucity of such instruments.
Khalil Aburezq , László Kasik
doaj  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Negative consequences

open access: yes
Peer ...
Beata Segercrantz, Karl-Erik Sveiby
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Negative Effects of Student Mobility: Mobility as a Predictor, Mobility as a Mediator

open access: yesInternational Journal of Education Policy and Leadership, 2013
Policy discussions on how to improve educational outcomes have traditionally focused on schools and teachers. While schools and teachers have measurable effects on educational outcomes, reforms aimed at only improving schools and teachers have failed to ...
Jimmy Scherrer
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy