Results 91 to 100 of about 91,779 (296)

Adverbial clauses and adverbial concord [PDF]

open access: yes, 2019
This paper speculates that the merge site of an adverbial clause, i.e. its external syntax, is determined by its derivational history, i.e. its internal syntax.
Endo, Yoshio, Haegeman, Liliane
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

On negation in yes/no questions in Serbo-Croatian [PDF]

open access: yes, 2006
The phenomenon discussed in this paper is the so-called expletive negation in negated yes/no questions in Serbo-Croatian. The term expletive negation seems, at this point to be a useful descriptive term for the phenomenon in question. One of the goals of
Milicevic, Natasa
core  

Negative concord in Washo as negative agreement

open access: yesProceedings of the Linguistic Society of America, 2019
Washo, a Native American isolate, displays negative concord morphology in the context of negation. Negative concord in Washo comes in the form of the morpheme -Na, which may be suffixed onto optionally many sentential elements in a single clause. Given the apparent lack of semantic contribution by this morpheme, I argue - building on accounts along the
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Immaginario del mare e homonoia. Luoghi reali e virtuali dell’armonia e dell’amicizia nella retorica politica e nella prassi (IV sec. a.C.)

open access: yesHistorika : Studi di Storia Greca e Romana, 2016
Concord is order, harmony, balance, it is a moral principle that inspires pacific coexistence within the civic community; this is the image delivered by IV century philosophical and political thought. Such a notion was developed within a speculation over
Giovanna Daverio Rocchi
doaj   +1 more source

Manchester Snow Emergency Analysis: Who is Being Towed from Where and Why [PDF]

open access: yes, 2015
This Capstone paper analyzes the City of Manchester, New Hampshire’s policy and community impacts when their Towing Snow Emergency procedures are implemented.
Pelletier, Michael James
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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