Results 71 to 80 of about 1,088 (233)

Feature reanalysis and the Latin origin of Romance Negative Concord

open access: yes, 2021
This chapter investigates the sequence of changes leading from the Latin system of negation to the various Romance outcomes. While Classical Latin is a Double Negation language, the earliest Romance varieties show a Concord grammar.
Chiara Gianollo, Gianollo Chiara
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Inter- vs. Intra-Speaker Variation in Mixed Heritage Syntax: A Statistical Analysis

open access: yesFrontiers in Psychology, 2019
Based on the novel data pertaining to five syntactic phenomena (the position of the finite verb in embedded clauses, in sentences with a modal verb, negative concord, the position of focused light/heavy objects in main clauses with a complex tense and ...
Federica Cognola   +2 more
doaj   +1 more source

Negative concord in Romanian as polyadic quantification

open access: yes, 2009
In this paper we develop an HPSG syntax-semantics of negative concord in Romanian. We show that n-words in Romanian can best be treated as negative quantifiers which may combine by resumption to form polyadic negative quantifiers.
Richter, Frank, Iordăchioaia, Gianina
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A register approach to negative concord versus negative polarity items in English

open access: yesLinguistics
Negative concord (NC) is used in many English varieties but usually considered ungrammatical in ‘standard’ contemporary English, where negative polarity items (NPIs) are used.
Rotter Stephanie, Liu Mingya
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Mehrsprachigkeit in Rio Grande do Sul: Zur Negation im Brasilianischen Hunsrückisch

open access: yesPandaemonium Germanicum: Revista de Estudos Germanísticos, 2023
Im vorliegenden Artikel wird anhand eines spontansprachlichen Korpus bilingualer Sprecher ein sprachliches Phänomen im brasilianischen Hunsrückischen genauer betrachtet: die Negation.
Esther Rinke, Cristina Flores
doaj  

Unnaturalness of Negation – an Old Wives’ Tale Retold

open access: yesELOPE, 2006
Negation has a very long history of study. In the realm of logic, negation is seen as a simple operation that turns an affirmative to a negative. This assumption strongly affected the linguistic study of negation, and led to some misconceptions.
Gašper Ilc
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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