Results 61 to 70 of about 1,088 (233)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Asymmetries in the Acceptability and Felicity of English Negative Dependencies: Where Negative Concord and Negative Polarity (Do Not) Overlap

open access: yesFrontiers in Psychology, 2019
Negative Concord (NC) constructions such as the news anchor didn’t warn nobody about the floods (meaning “the news anchor warned nobody”), in which two syntactic negations contribute a single semantic one, are stigmatized in English, while their Negative
Frances Blanchette, Cynthia Lukyanenko
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

THE FOCAL STRUCTURE IN MANDARIN VP-ELLIPSIS: A CROSS-LINGUISTIC PERSPECTIVE [PDF]

open access: yesTaiwan Journal of Linguistics, 2009
This paper argues that Soh’s (2007) ΣP analysis only partially explains polarity operation in Mandarin VP-ellipsis. With new examples of the use of the particle que ‘however’, a polarity contrast of ye ‘also’, we propose that there are two focus ...
Ting-Chi Wei
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Negative Dependencies in Turkish

open access: yesLanguages
In this paper, we provide an overview of negative dependencies in Turkish. The first are elements such as hiçkimse, which sometimes seem to mean ‘anybody’ and sometimes ‘nobody’.
Beste Kamali, Hedde Zeijlstra
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Nie sommer nie: Sociohistorical and formal comparative considerations in the rise and maintenance of the modern Afrikaans negation system

open access: yesStellenbosch Papers in Linguistics Plus, 2015
This article has three major objectives. Firstly, it aims to describe and account for the peculiarity of the modern Afrikaans negative concord marker nie2 in the familiar Western European context.
Biberauer, Theresa
doaj   +1 more source

Negative concord in Levantine Arabic [PDF]

open access: yes, 2011
textThis dissertation is a study of negative concord in Levantine Arabic (Israel/Palestine, Jordan, Lebanon, Syria), where negative concord is the failure of an n-word to express negative meaning distinctly when in syntagm with another negative ...
Hoyt, Frederick MacNeill
core  

Distinguishing negative polarity from concord in Korean

open access: yes, 2013
Distinguishing negative polarity from concord in ...
Kang, Jungmin, Tieu, Lyn Shan
core   +1 more source

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