Results 51 to 60 of about 16,841 (212)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Negative Dependencies in Turkish
LanguagesIn this paper, we provide an overview of negative dependencies in Turkish. The first are elements such as hiçkimse, which sometimes seem to mean ‘anybody’ and sometimes ‘nobody’.
Beste Kamali, Hedde Zeijlstra
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Stellenbosch Papers in Linguistics Plus, 2015 This article has three major objectives. Firstly, it aims to describe and account for the peculiarity of the modern Afrikaans negative concord marker nie2 in the familiar Western European context.
Biberauer, Theresa
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A register approach to negative concord versus negative polarity items in English
LinguisticsNegative concord (NC) is used in many English varieties but usually considered ungrammatical in ‘standard’ contemporary English, where negative polarity items (NPIs) are used.
Rotter Stephanie, Liu Mingya
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Unnaturalness of Negation – an Old Wives’ Tale Retold
ELOPE, 2006 Negation has a very long history of study. In the realm of logic, negation is seen as a simple operation that turns an affirmative to a negative. This assumption strongly affected the linguistic study of negation, and led to some misconceptions.
Gašper Ilc
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Mehrsprachigkeit in Rio Grande do Sul: Zur Negation im Brasilianischen Hunsrückisch
Pandaemonium Germanicum: Revista de Estudos Germanísticos, 2023 Im vorliegenden Artikel wird anhand eines spontansprachlichen Korpus bilingualer Sprecher ein sprachliches Phänomen im brasilianischen Hunsrückischen genauer betrachtet: die Negation.
Esther Rinke, Cristina Flores
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Inter- vs. Intra-Speaker Variation in Mixed Heritage Syntax: A Statistical Analysis
Frontiers in Psychology, 2019 Based on the novel data pertaining to five syntactic phenomena (the position of the finite verb in embedded clauses, in sentences with a modal verb, negative concord, the position of focused light/heavy objects in main clauses with a complex tense and ...
Federica Cognola +2 more
doaj +1 more source