Results 51 to 60 of about 16,232 (241)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

THE FOCAL STRUCTURE IN MANDARIN VP-ELLIPSIS: A CROSS-LINGUISTIC PERSPECTIVE [PDF]

Taiwan Journal of Linguistics, 2009
This paper argues that Soh’s (2007) ΣP analysis only partially explains polarity operation in Mandarin VP-ellipsis. With new examples of the use of the particle que ‘however’, a polarity contrast of ye ‘also’, we propose that there are two focus ...
Ting-Chi Wei
doaj  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Negative Dependencies in Turkish

Languages
In this paper, we provide an overview of negative dependencies in Turkish. The first are elements such as hiçkimse, which sometimes seem to mean ‘anybody’ and sometimes ‘nobody’.
Beste Kamali, Hedde Zeijlstra
doaj   +1 more source

Nie sommer nie: Sociohistorical and formal comparative considerations in the rise and maintenance of the modern Afrikaans negation system

Stellenbosch Papers in Linguistics Plus, 2015
This article has three major objectives. Firstly, it aims to describe and account for the peculiarity of the modern Afrikaans negative concord marker nie2 in the familiar Western European context.
Biberauer, Theresa
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The Negative Concord Mystery: Insights from a Language Model

Information
An important recent development in the field of linguistics is the use of small language models to investigate language acquisition. Following this line of research, we investigate the mysterious appearance of ‘negative concord’ (e.g., I didn’t do ...
William O’Grady, Haopeng Zhang, Miseon Lee   +2 more
doaj   +1 more source

Inter- vs. Intra-Speaker Variation in Mixed Heritage Syntax: A Statistical Analysis

Frontiers in Psychology, 2019
Based on the novel data pertaining to five syntactic phenomena (the position of the finite verb in embedded clauses, in sentences with a modal verb, negative concord, the position of focused light/heavy objects in main clauses with a complex tense and ...
Federica Cognola, Ivano Baronchelli, Evelina Molinari   +2 more
doaj   +1 more source