Results 71 to 80 of about 131,244 (292)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Area demand quantification for energy system-integrated negative emissions based on carbon dioxide removal portfolios

open access: yesEnvironmental Research Letters
Climate change mitigation will most likely rely on large-scale carbon dioxide removal (CDR). Often, only a few technology options are used, principally bioenergy, carbon capture and sequestration, as well as afforestation and reforestation.
Dominik Keiner   +3 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Ocean liming can help achieve the Paris climate target

open access: yesEnvironmental Research Letters
To stabilize global mean temperature and stay below critical thresholds, deep emission reductions have to be complemented with carbon dioxide removal. A broad portfolio of options is necessary to enable sufficient potential and mitigate sustainability ...
Jessica Strefler   +4 more
doaj   +1 more source

Auctioning Greenhouse Gas Emissions Permits in Australia [PDF]

open access: yes
The allocation of permits is an important design aspect of an emissions trading scheme. Traditionally, governments have favoured the free allocation of greenhouse gas permits based on individual historical emissions (‘grandfathering’) or industry ...
Peter Cramton   +3 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

The influence of foreign vs. North American emissions on surface ozone in the US. [PDF]

open access: yes, 2009
As part of the Hemispheric Transport of Air Pollution (HTAP; http:// www.htap.org) project, we analyze results from 15 global and 1 hemispheric chemical transport models and compare these to Clean Air Status and Trends Network (CASTNet) observations in ...
C. Cuvelier   +62 more
core   +1 more source

Negative carbon dioxide emissions [PDF]

open access: yesPhysics Today, 2020
As the world continues to spew carbon dioxide at record levels, it’s becoming clear that emissions reductions alone can’t prevent the greenhouse gas from rising to dangerous levels.
openaire   +1 more source

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