Results 91 to 100 of about 5,295,174 (295)
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Negative feedback and physical limits of genes [PDF]
Journal of Theoretical Biology, 2011 17 pages, 7 figures, 1 ...
openaire +6 more sources
Accurate prediction of gene feedback circuit behavior from component properties [PDF]
, 2007 A basic assumption underlying synthetic biology is that analysis of genetic circuit elements, such as regulatory proteins and promoters, can be used to understand and predict the behavior of circuits containing those elements. To test this assumption, we
Uri Alon +12 more
core +1 more source
FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Sensors, 2017 Electrochemical seismic sensors are key components in monitoring ground vibration, which are featured with high performances in the low-frequency domain.
Guanglei Li +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
An Indirect Method and Equipment for Temperature Monitoring and Control
Advances in Electrical and Computer Engineering, 2015 A new temperature control method for a metallic filament used at high temperature values is proposed by the authors in this paper. The filament used is heated by a switch mode power supply built around a step-down converter.
ETZ, R. +4 more
doaj +1 more source
Angular Molecular–Electronic Sensor with Negative Magnetohydrodynamic Feedback
Sensors, 2018 A high-precision angular accelerometer based on molecular–electronic transfer (MET) technology with a high dynamic range and a low level of self-noise has been developed.
Egor Egorov +3 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Frontiers in Human Neuroscience, 2015 The current study compared the effects of informative and confirmatory feedback on brain activation during negative feedback processing. For confirmatory feedback trials, participants were informed that they had failed the task, whereas informative ...
Yeon-Kyoung eWoo +5 more
doaj +1 more source