Results 81 to 90 of about 702,888 (304)
Dynamics of a state-dependent delay-differential equation
Electronic Journal of Qualitative Theory of Differential EquationsWe present a detailed study of a scalar differential equation with threshold state-dependent delayed feedback. This equation arises as a simplification of a gene regulatory model.
Tomas Gedeon +4 more
doaj +1 more source
Evolutionary Selection of Expectations in Positive and Negative Feedback Markets [PDF]
An economic environment is a feedback system, where dynamics of aggregate variables depend on individual expectations and also shape them. The type of feedback mechanism is crucial for the aggregate outcome.
Philipse, R., Hommes, C.H., Anufriev, M.
core
Negative volatility spillovers in the unrestricted ECCC-GARCH model [PDF]
, 2010 Copyright @ 2010 Cambridge University Press.This paper considers a formulation of the extended constant or time-varying conditional correlation GARCH model that allows for volatility feedback of either the positive or negative sign.
Karanasos, Menelaos +3 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Is identity per se irrelevant? A contrarian view of self-verification effects
, 2008 Self-verification theory (SVT) posits that people who hold negative self-views, such as depressive patients, ironically strive to verify that these self-views are correct, by actively seeking out critical feedback or interaction partners who evaluate ...
Gregg, Aiden P.
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
How leaders can use negative feedback to their advantage.
, 2017 This short article explores how leaders can use negative feedback to their advantage by identifying their weaknesses andturning them into strengths. In order to enable their peers to give them true feedback, leaders should nurture a safeenvironment of ...
Papasava, Angeliki
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
The stability and electromagnetic compatibility of power supply modules and systems
Физика волновых процессов и радиотехнические системы, 2017 The main questions for designing the power supply modules and systems are considered. They are the electromagnetic compatibility of power supply modules, the stability of power supply modules and the stability of whole power supply system.
V.F. Dmitrikov +3 more
doaj