Results 61 to 70 of about 5,295,174 (295)
Mean field analysis of a spatial stochastic model of a gene regulatory network [PDF]
, 2015 A gene regulatory network may be defined as a collection of DNA segments which interact with each other indirectly through their RNA and protein products.
Murray, P. J. +3 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Effect of Learners’ Proficiency on the Provision of Implicit Negative Feedback and Its Incorporation in the Interaction between Non-native Speakers of English [PDF]
, 2005 This research proposal will investigate the effect of learners’ proficiency on the provision of implicit negative feedback and the incorporation of the feedback.
Kim, Yong Hwan
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Feedback Regulation of Pancreatic Juice Secretion in Pigs
BiomoleculesPancreatic exocrine secretion is regulated by the physicochemical properties and nutrient composition of gastric and intestinal chyme. The present study examined integrative feedback mechanisms involved in the physiological control of pancreatic ...
Jose Luis Valverde Piedra +1 more
doaj +1 more source
Mysteries of TGF-β paradox in benign and malignant cells
Frontiers in Oncology, 2014 TGF-β regulates a wide range of biological functions including embryonic development, wound healing, organogenesis, immune modulation, and cancer progression. Interestingly, TGF-β is known to inhibit cell growth in benign cells but promote progression in
Chung eLee, Chung eLee, Chung eLee
doaj +1 more source
Peer feedback content and sender’s competence level in academic writing revision tasks: Are they critical for feedback perceptions and efficiency? [PDF]
, 2010 Peer feedback content is a core component of peer assessment, but the impact of various contents of feedback is hardly studied. Participants in the study were 89 graduate students who were assigned to four experimental and a control group.
Strijbos, Jan Willem +3 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
DANG: Decoupled Adaptive Normalized Graph Convolutional Network for Sign-Aware Recommendation
IEEE AccessGraph Neural Networks (GNNs) are widely used in recommendation systems, but most methods focus solely on positive feedback, neglecting the avoidance preferences inherent in negative interactions.
Zongjian Lv, Youxi Luo
doaj +1 more source
Facing Cold-Start: A Live TV Recommender System Based on Neural Networks
IEEE Access, 2020 With the increase in the number of live TV channels, audiences must spend increasing amounts of time and energy deciding which shows to watch; this problem is called information overload, and recommender systems (RSs) are effective methods for addressing
Xiaosong Zhu +3 more
doaj +1 more source