Results 51 to 60 of about 702,888 (304)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Data‐driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states

open access: yesMolecular Systems Biology, 2014
The extracellular signal‐regulated kinase (ERK) signaling pathway controls cell proliferation and differentiation in metazoans. Two hallmarks of its dynamics are adaptation of ERK phosphorylation, which has been linked to negative feedback, and ...
Shoeb Ahmed   +6 more
doaj   +1 more source

NEGATIVE FEEDBACKS IN THE ECONOMY AND INDUSTRIAL LOCATION* [PDF]

open access: yesJournal of Regional Science, 1996
ABSTRACT. Incorporating regional asymmetry and negative feedbacks (congestion) in a model of economic geography and international trade shows that complete specialization of production at one location is unlikely. We identify an agglomerating force: the home market effect, and two spreading forces, competition for demand from immobile sectors of ...
BRAKMAN, S.   +4 more
openaire   +5 more sources

An effective model of using negative relevance feedback for information filtering [PDF]

open access: yes, 2009
Over the years, people have often held the hypothesis that negative feedback should be very useful for largely improving the performance of information filtering systems; however, we have not obtained very effective models to support this hypothesis ...
Abdulmohsen Algarni   +8 more
core   +1 more source

Designing negative feedback loops in enzymatic coacervate droplets

open access: yes, 2022
Membraneless organelles within the living cell use phase separation of biomolecules coupled with enzymatic reactions to regulate cellular processes. The diverse functions of these biomolecular condensates motivate the pursuit of simpler in vitro models ...
Nisha, Modi   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Feedback Stability of Negative Imaginary Systems [PDF]

open access: yesIEEE Transactions on Automatic Control, 2017
This paper extends the robust feedback stability theorem of negative imaginary systems by removing restrictive assumptions on the instantaneous gains of the systems that were imposed in the earlier literature, and it further generalises this robust analysis result into the case that allows negative imaginary systems to have poles at the origin.
Alexander Lanzon, Hsueh-Ju Chen
openaire   +2 more sources

The Effect of Learners’ Proficiency on the Provision of Implicit Negative Feedback and Its Incorporation in the Interaction between Non-native Speakers of English [PDF]

open access: yes, 2005
This research proposal will investigate the effect of learners’ proficiency on the provision of implicit negative feedback and the incorporation of the feedback.
Kim, Yong Hwan
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Executive dynamic scheduling algorithm based on high-order heterogeneity

open access: yesTongxin xuebao, 2022
At present, most isomer scheduling models in DHR systems only considered second-order isomerism and lack dynamics.In order to solve these problems, a dynamic scheduling algorithm was proposed, which combined heterogeneity and dynamics by determining a ...
Hongyong JIA   +4 more
doaj  

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